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Table 1 Microbiological profile and antibiotic resistance pattern of isolates from patient with infective endocarditis received at the AKUH clinical laboratory (n = 104)

From: Microbiological and clinical profile of infective endocarditis patients: an observational study experience from tertiary care center Karachi Pakistan

Microorganism Total number cases n = 104(%) Percent resistance of antibiotic for the species
CN CI ER PE VA CH OX CP AM CR
Gram positive organism 68 (65.4)  
Staphylococcus species 24 (23.1)           
•S. aureus 18 (17.3) 27.0 22.2 50.0 100 00 00 77. 44.4
  MSSA 4 (3.8)           
  MRSA 14 (13.5)           
CONS 6 (5.8) 16.6 16.6 33.3 100 00 00 83.3 60.0
Streptococcus species 36 (34.7) NP 20.0 40.0 14.2 00 02.8
•S. pneumoniae 2 (1.9)           
•S. mitis 8 (7.7)           
•S. oralis 5 (4.8)           
•S. sanguis 3 (2.9)           
•S. viridans 3 (2.9)           
•S. milleri 1 (1.0)           
•S. bovis 3 (2.9)           
•Streptococcus species 5 (4.8)           
•Granulicatella adiacens 1 (1.0)           
•Aerococcus viridans 2 (1.9)           
•Gemella haemolysan 1 (1.0)           
Enterococcus species 4 (3.8) 25.0 50.0 50.0 00 25.0 50.0
Corynebaterium species 4 (3.8) 25 00 00 00 25.0 00  
Gram negative organism 3 (2.9) 00 33.3 00
Haemophilus actinomycetemcomitans, Klebsiella pneumoniae, Acinetobacter species.            
Fungus 3 (2.9) No resistance to azoles and Amphotericin
Candida albicans, Aspergillus niger, Fusarium species   
Culture negative cases 30 (28.8)
  1. CN Gentamicin, CI Clindamycin, ER Erythromycin, PE Penicillin, VA Vancomycin, CH Chloramphenicol, OX Oxacillin, CP Ciprofloxacin CR Ceftriaxone, MRSA Methicillin resistant Staphylococcus aureus, MSSA Methicillin-Sensitive Staphylococcus aureus