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Table 2 Univariate Analysis of positive pulmonary and mediastinal lymph nodes (pN1+, pN2+)

From: Predictive risk factors for lymph node metastasis in patients with resected non-small cell lung cancer: a case control study

Variables pN1- (%) pN1+ (%) P-Value pN2- (%) pN2+ (%) P-Value
Sex 0.148   0.627
 male 90 (63.4) 52 (36.6) 112 (78.9) 30 (21.1)
 female 46 (74.2) 16 (25.8) 47 (75.8) 15 (24.2)
Age 0.298   0.237
  ≤ 68 years 68 (63) 40 (37) 88 (81.5) 20 (81.5)
  > 68 years 68 (70.8) 28 (29.2) 71 (74.0) 25 (21.2)
Tumor site 0.067   0.783
 right 90 (71.4) 36 (28.6) 99 (78.6) 27 (21.4)
 left 46 (59) 32 (41) 60 (76.9) 18 (23.1)
Tumor localization < 0.001   0.02
 central 25 (47.2) 28 (52.8) 36 (66.7) 18 (33.3)
 peripheral 111 (74.5) 38 (25.5) 122 (81.9) 27 (18.1)
Tumor size 0.011   0.042
  ≤ 3 cm 77 (75.5) 25 (24.5) 86 (84.3) 16 (15.7)
  > 3 cm 59 (57.8) 43 (42.8) 73 (71.6) 29 (28.4)
Lobe distribution 0.918   0.385
 ULa 85 (66.4) 43 (33.6) 97 (75.8) 31 (24.2)
 Non-UL 51 (67.1) 25 (32.9) 62 (81.6) 14 (18.4)
pT-category 0.015   0.081
 pT1 70 (77.8) 20 (22.2) 77 (85.6) 13 (14.4)
 pT2 33 (61.1) 21 (38.9) 40 (74.1) 14 (25.9)
 pT3 18 (51.4) 17 (48.6) 23 (65.7) 12 (34.3)
 pT4 13 (56.5) 10 (43.5) 17 (73.9) 6 (26.1)
pR-classification 0.017   0.088
 R0 130 (68.8) 59 (31.2) 150 (79.4) 39 (20.6)
 R1–2 5 (35.7) 9 (64.3) 8 (57.1) 6 (42.9)
pL-status < 0.001   < 0.001
 pL0 55 (96.5) 2 (3.5) 56 (98.2) 1 (1.8)
 pL1 80 (54.8) 66 (45.2) 102 (69.9) 44 (30.1)
pV-status 0.006   0.004
 pV0 117 (70.9) 48 (29.1) 135 (81.1) 30 (18.2)
 pV 18 (47.4) 20 (52.6) 23 (60.5) 15 (39.5)
Pn-Status 0.088   0.34
 Pn0 131 (67.9) 62 (32.1) 149 (77.2) 44 (22.8)
 Pn1 4 (40.0) 6 (60.0) 9 (90.0) 1 (10.0)
Histological tumor type 0.214   0.646
 Adeno-Ca.b 84 (71.8) 33 (28.2) 94 (80.3) 23 (19.7)
56 (74.4) 19 (25.6)
 SCCc 45 (60.0) 30 (40.0) 9 (75.0) 3 (25.0)
 others 7 (58.3) 5 (41.7)
Grading 0.016   0.001
 G1 25 (89.3) 3 (10.7) 27 (96.4) 1 (3.6)
 G2 64 (67.4) 31 (32.6) 79 (83.2) 16 (16.8)
 G3 39 (57.4) 29 (42.6) 43 (63.2) 25 (36.8)
 G4 7 (58.3) 5 (41.7) 9 (75.0) 3 (25.0)
  1. aUL Upper lobe,b Adeno-Ca. Adenocarcinoma , cSCC Squamous cell carcinoma