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Table 2 Univariate Analysis of positive pulmonary and mediastinal lymph nodes (pN1+, pN2+)

From: Predictive risk factors for lymph node metastasis in patients with resected non-small cell lung cancer: a case control study

Variables

pN1- (%)

pN1+ (%)

P-Value

pN2- (%)

pN2+ (%)

P-Value

Sex

0.148

 

0.627

 male

90 (63.4)

52 (36.6)

112 (78.9)

30 (21.1)

 female

46 (74.2)

16 (25.8)

47 (75.8)

15 (24.2)

Age

0.298

 

0.237

  ≤ 68 years

68 (63)

40 (37)

88 (81.5)

20 (81.5)

  > 68 years

68 (70.8)

28 (29.2)

71 (74.0)

25 (21.2)

Tumor site

0.067

 

0.783

 right

90 (71.4)

36 (28.6)

99 (78.6)

27 (21.4)

 left

46 (59)

32 (41)

60 (76.9)

18 (23.1)

Tumor localization

< 0.001

 

0.02

 central

25 (47.2)

28 (52.8)

36 (66.7)

18 (33.3)

 peripheral

111 (74.5)

38 (25.5)

122 (81.9)

27 (18.1)

Tumor size

0.011

 

0.042

  ≤ 3 cm

77 (75.5)

25 (24.5)

86 (84.3)

16 (15.7)

  > 3 cm

59 (57.8)

43 (42.8)

73 (71.6)

29 (28.4)

Lobe distribution

0.918

 

0.385

 ULa

85 (66.4)

43 (33.6)

97 (75.8)

31 (24.2)

 Non-UL

51 (67.1)

25 (32.9)

62 (81.6)

14 (18.4)

pT-category

0.015

 

0.081

 pT1

70 (77.8)

20 (22.2)

77 (85.6)

13 (14.4)

 pT2

33 (61.1)

21 (38.9)

40 (74.1)

14 (25.9)

 pT3

18 (51.4)

17 (48.6)

23 (65.7)

12 (34.3)

 pT4

13 (56.5)

10 (43.5)

17 (73.9)

6 (26.1)

pR-classification

0.017

 

0.088

 R0

130 (68.8)

59 (31.2)

150 (79.4)

39 (20.6)

 R1–2

5 (35.7)

9 (64.3)

8 (57.1)

6 (42.9)

pL-status

< 0.001

 

< 0.001

 pL0

55 (96.5)

2 (3.5)

56 (98.2)

1 (1.8)

 pL1

80 (54.8)

66 (45.2)

102 (69.9)

44 (30.1)

pV-status

0.006

 

0.004

 pV0

117 (70.9)

48 (29.1)

135 (81.1)

30 (18.2)

 pV

18 (47.4)

20 (52.6)

23 (60.5)

15 (39.5)

Pn-Status

0.088

 

0.34

 Pn0

131 (67.9)

62 (32.1)

149 (77.2)

44 (22.8)

 Pn1

4 (40.0)

6 (60.0)

9 (90.0)

1 (10.0)

Histological tumor type

0.214

 

0.646

 Adeno-Ca.b

84 (71.8)

33 (28.2)

94 (80.3)

23 (19.7)

56 (74.4)

19 (25.6)

 SCCc

45 (60.0)

30 (40.0)

9 (75.0)

3 (25.0)

 others

7 (58.3)

5 (41.7)

Grading

0.016

 

0.001

 G1

25 (89.3)

3 (10.7)

27 (96.4)

1 (3.6)

 G2

64 (67.4)

31 (32.6)

79 (83.2)

16 (16.8)

 G3

39 (57.4)

29 (42.6)

43 (63.2)

25 (36.8)

 G4

7 (58.3)

5 (41.7)

9 (75.0)

3 (25.0)

  1. aUL Upper lobe,b Adeno-Ca. Adenocarcinoma , cSCC Squamous cell carcinoma