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Table 2 Univariate analysis of risk factors associated with postoperative AKI in patients with ADTIAD

From: Cardiopulmonary bypass time is an independent risk factor for acute kidney injury in emergent thoracic aortic surgery: a retrospective cohort study

Variable Statistics OR (95%CI) P-value
Age (year) 47.8 ± 10.7 1.02 (0.98, 1.05) 0.339
Gender
 male 86 (74.78%) 1.0  
 female 29 (25.22%) 1.35 (0.58, 3.17) 0.487
BMI (kg/m2) 26.2 ± 3.9 1.18 (1.06, 1.33) 0.003
Diabetes mellitus 7 (6.09%) 5.78 (0.67, 49.62) 0.110
Hypertension 92 (80.00%) 1.30 (0.52, 3.24) 0.576
Previous cerebrovascular disease 6 (5.22%) 0.42 (0.07, 2.41) 0.333
Coronary artery disease 6 (5.22%) 0.88 (0.17, 4.55) 0.878
Smoking history 56 (48.70%) 1.83 (0.87, 3.85) 0.110
Drinking history 23 (20.00%) 0.96 (0.38, 2.39) 0.926
Hemopericardium 19 (16.52%) 0.98 (0.37, 2.63) 0.969
BUN (mmol/L) 7.2 ± 2.5 1.03 (0.89, 1.19) 0.722
Preoperative sCr (umol/L) 86.2 ± 29.07 1.01 (1.00, 1.02) 0.147
eGFR mL/(min·1.73m2) 88.6 ± 22.6 0.98 (0.96, 1.00) 0.013
Hemoglobin (g/L) 136.5 ± 17.3 1.00 (0.97, 1.02) 0.686
Hematocrit (%) 39.4 ± 4.6 0.97 (0.89, 1.05) 0.440
LVEF (%) 62.9 ± 6.1 1.03 (0.97, 1.10) 0.354
Renal artery dissection or occlusion 17 (14.8%) 0.57 (0.20, 1.62) 0.292
Penn class
 Class Aa 70 (60.9%) 1.0  
 Non class Aa 45 (39.1%) 1.18 (0.56, 2.50) 0.665
Kidney malperfusion 7 (6.1%) 1.19 (0.25, 5.59) 0.823
AMI 9 (7.8%) 3.37 (0.67, 16.98) 0.141
Preoperative shock 19 (16.5%) 0.98 (0.37, 2.63) 0.969
CPB time 211 ± 56 1.09 (1.01, 1.17) 0.032
Aortic cross clamp time (min) 123.8 ± 42.6 1.00 (0.99, 1.01) 0.401
Bentall+TAR+FET 47 (40.9%) 1.01 (0.48,2.13) 0.979
Combined with CABG 8 (7.0%) 1.52 (0.35, 6.67) 0.581
Combined with aortic bypass surgery 1 (0.9%) a 0.992
Circulatory arrest time (min) 27.4 ± 8.5 1.00 (0.96, 1.05) 0.913
Nasopharyngeal temperature (°C) at circulatory arrest 22.9 ± 1.6 0.83 (0.65, 1.06) 0.143
Rectal temperature (°C) at circulatory arrest 25.3 ± 2.1 0.92 (0.77, 1.10) 0.356
Intraoperative transfusion of PRBCs 73 (63.5%) 0.90 (0.42, 1.92) 0.779
Reoperation for bleeding 9 (7.83%) 8.00 (0.97, 66.21) 0.054
  1. Results are expressed as n (%) or mean ± SD or median [IQR]
  2. AKI acute kidney injury, ADTIAD acute DeBakey Type I aortic dissection, AMI acute myocardial infarction, BMI body mass index, BUN blood urea nitrogen, CABG coronary artery bypass grafting, CPB cardiopulmonary bypass, eGFR estimated glomerular filtration rate, FET frozen elephant trunk, TAR total arch replacement, LVEF left ventricular ejection fraction, PRBCs packed red blood cells, sCr serum creatinine, SD standard deviation, IOR interquartile range
  3. Bold value indicates significance at p < 0.05
  4. aThe result failed because of the small sample size