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Table 2 Univariate analysis of risk factors associated with postoperative AKI in patients with ADTIAD

From: Cardiopulmonary bypass time is an independent risk factor for acute kidney injury in emergent thoracic aortic surgery: a retrospective cohort study

Variable

Statistics

OR (95%CI)

P-value

Age (year)

47.8 ± 10.7

1.02 (0.98, 1.05)

0.339

Gender

 male

86 (74.78%)

1.0

 

 female

29 (25.22%)

1.35 (0.58, 3.17)

0.487

BMI (kg/m2)

26.2 ± 3.9

1.18 (1.06, 1.33)

0.003

Diabetes mellitus

7 (6.09%)

5.78 (0.67, 49.62)

0.110

Hypertension

92 (80.00%)

1.30 (0.52, 3.24)

0.576

Previous cerebrovascular disease

6 (5.22%)

0.42 (0.07, 2.41)

0.333

Coronary artery disease

6 (5.22%)

0.88 (0.17, 4.55)

0.878

Smoking history

56 (48.70%)

1.83 (0.87, 3.85)

0.110

Drinking history

23 (20.00%)

0.96 (0.38, 2.39)

0.926

Hemopericardium

19 (16.52%)

0.98 (0.37, 2.63)

0.969

BUN (mmol/L)

7.2 ± 2.5

1.03 (0.89, 1.19)

0.722

Preoperative sCr (umol/L)

86.2 ± 29.07

1.01 (1.00, 1.02)

0.147

eGFR mL/(min·1.73m2)

88.6 ± 22.6

0.98 (0.96, 1.00)

0.013

Hemoglobin (g/L)

136.5 ± 17.3

1.00 (0.97, 1.02)

0.686

Hematocrit (%)

39.4 ± 4.6

0.97 (0.89, 1.05)

0.440

LVEF (%)

62.9 ± 6.1

1.03 (0.97, 1.10)

0.354

Renal artery dissection or occlusion

17 (14.8%)

0.57 (0.20, 1.62)

0.292

Penn class

 Class Aa

70 (60.9%)

1.0

 

 Non class Aa

45 (39.1%)

1.18 (0.56, 2.50)

0.665

Kidney malperfusion

7 (6.1%)

1.19 (0.25, 5.59)

0.823

AMI

9 (7.8%)

3.37 (0.67, 16.98)

0.141

Preoperative shock

19 (16.5%)

0.98 (0.37, 2.63)

0.969

CPB time

211 ± 56

1.09 (1.01, 1.17)

0.032

Aortic cross clamp time (min)

123.8 ± 42.6

1.00 (0.99, 1.01)

0.401

Bentall+TAR+FET

47 (40.9%)

1.01 (0.48,2.13)

0.979

Combined with CABG

8 (7.0%)

1.52 (0.35, 6.67)

0.581

Combined with aortic bypass surgery

1 (0.9%)

a

0.992

Circulatory arrest time (min)

27.4 ± 8.5

1.00 (0.96, 1.05)

0.913

Nasopharyngeal temperature (°C) at circulatory arrest

22.9 ± 1.6

0.83 (0.65, 1.06)

0.143

Rectal temperature (°C) at circulatory arrest

25.3 ± 2.1

0.92 (0.77, 1.10)

0.356

Intraoperative transfusion of PRBCs

73 (63.5%)

0.90 (0.42, 1.92)

0.779

Reoperation for bleeding

9 (7.83%)

8.00 (0.97, 66.21)

0.054

  1. Results are expressed as n (%) or mean ± SD or median [IQR]
  2. AKI acute kidney injury, ADTIAD acute DeBakey Type I aortic dissection, AMI acute myocardial infarction, BMI body mass index, BUN blood urea nitrogen, CABG coronary artery bypass grafting, CPB cardiopulmonary bypass, eGFR estimated glomerular filtration rate, FET frozen elephant trunk, TAR total arch replacement, LVEF left ventricular ejection fraction, PRBCs packed red blood cells, sCr serum creatinine, SD standard deviation, IOR interquartile range
  3. Bold value indicates significance at p < 0.05
  4. aThe result failed because of the small sample size