Table 1 Baseline Data
Baseline patient characteristics | ||||
|---|---|---|---|---|
Whole group (n = 112) | RHF pre OP (n = 72) | No RHF pre OP (n = 40) | p-value | |
Age | 55.3 (12.5) | 53.0 (12.4) | 59.6 (11.7) | 0.007 |
Male | 98 (87.5) | 63 (87.5) | 35 (87.5) | 1.000 |
BMI | 26.5 (4.5) | 27.0 (3.8) | 26.1 (5.0) | 0.400 |
INTERMACS | ||||
▪ 1–2 | 49 (43.8) | 42 (58.3) | 7 (17.5) | |
▪ 3–4 | 40 (35.7) | 19 (26.4) | 21 (52.5) | |
▪ 5–7 | 23 (20.5) | 11 (15.3) | 12 (30.0) | < 0.001 |
Indication for LVAD therapy | ||||
▪ BTT | 76 (67.9) | 50 (69.4) | 26 (65.0) | |
▪ DT | 31 (27.7) | 17 (23.6) | 14 (35.0) | |
▪ BTR | 3 (2.7) | 3 (4.3) | 0 (0.0) | |
▪ Emergency | 2 (1.8) | 2 (2.8) | 0 (0.0) | 0.379# |
Underlying disease | ||||
▪ Ischaemic cardiomyopathy | 39 (34.8) | 23 (31.9) | 16 (40.0) | |
▪ Dilated cardiomyopathy | 62 (55.4) | 39 (54.2) | 23 (57.5) | |
▪ Acute myocarditis | 4 (3.6) | 3 (4.2) | 1 (2.5) | |
▪ Postcardiotomy syndrome | 4 (3.6) | 4 (5.6) | 0 (0.0) | |
▪ Other/not known | 3 (2.7) | 3 (4.2) | 0 (0.0) | 0.834## |
Echocardiography | ||||
EF < 30%### | 107 (95.5) | 69 (95.8) | 38 (95.0) | 0.838 |
Moderate or severe mitral valve regurgitation | 52 (46.5) | 33 (45.8) | 19 (47.5) | 0.865 |
Moderate or severe tricuspid valve regurgitation | 45 (40.2) | 33 (45.8) | 12 (30.0) | 0.101 |
TAPSE | 14.6 (4.1) | 14.6 (4.4) | 14.6 (3.5) | 0.968 |
V. cava inferior diameter | 19.4 (4.1) | 19.4 (4.0) | 19.2 (4.4) | 0.758 |
Load adaption index (LAI) | 26.4 (9.1) | 25.5 (8.9) | 28.0 (9.5) | 0.161 |
Right Heart Catheter | ||||
PVR [Dyn*s/cm^5] | 227.6 (154.9) | 237.2 (186.5) | 216.8 (111.0) | 0.599 |
CI [L/min*m−2] | 1.9 (0.5) | 2.0 (0.6) | 1.8 (0.4) | 0.133 |
PAWP [mmHg] | 23.9 (10.3) | 24.2 (9.3) | 23.7 (11.4) | 0.847 |
mPAP [mmHg] | 31.4 (12.2) | 32.8 (11.4) | 30.0 (13.0) | 0.339 |
CVP [mmHg] | 10.8 (6.4) | 12.4 (6.6) | 9.1 (5.8) | 0.032 |
CVP/PAWP | 0.47 (0.25) | 0.54 (0.28) | 0.40 (0.18) | 0.026 |
Laboratory results | ||||
Hb [g/dL] | 11.3 (2.3) | 10.8 (2.1) | 12.1 (2.3) | 0.003 |
Leucocytes [Mrd/L] | 9.6 (5.1) | 10.2 (5.0) | 8.6 (5.0) | 0.113 |
Thrombocytes [Mrd/L] | 198.8 (91.2) | 193.0 (90.6) | 209.3 (90.4) | 0.367 |
Total Bilirubin [mg/dL] | 1.1 (1.1) | 1.3 (1.3) | 0.9 (0.5) | 0.018 |
Urea [mg/dL] | 35.2 (19.2) | 37.3 (21.4) | 31.5 (21.4) | 0.081 |
Creatinine [mg/dL] | 1.8 (0.9) | 1.9 (1.0) | 1.5 (0.6) | 0.020 |
GOT [U/L] | 185.1 (525.8) | 65.9 (114.9) | 251.3 (642.2) | 0.002 |
GPT [U/L] | 145.7 (384.3) | 193.7 (461.2) | 59.3 (145.3) | 0.025 |
GGT [U/L] | 137.5 (100.0) | 145.7 (109.7) | 122.7 (78.7) | 0.244 |
CRP [mg/L] | 36.3 (50.7) | 44.4 (57.4) | 21.8 (31.3) | 0.008 |
INR | 1.4 (0.5) | 1.3 (0.4) | 1.5 (0.7) | 0.222 |