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Table 1 Protocol for NSAID treatment

From: Surgical ligation of patent ductus arteriosus in preterm neonates weighing less than 1500g: a 9-year single center experience

Age at 1st dose1st2nd3rd
Indomethacin (mg/kg) a)
  < 48 h0.20.10.1
 2–7 days0.20.20.2
  > 7 days0.20.250.25
 Ibuprofen (mg/kg) b)1055
  1. NSAID nonsteroidal anti-inflammatory drug
  2. aAt 12- to 24-h intervals. bAt 24-h intervals