Table 5 Characteristics of the patients without acute aortic syndrome
No AKI | AKI Stage | P1 Value* | P2 Value# | |||
|---|---|---|---|---|---|---|
1 | 2 | 3 | ||||
Patient population (n) | 113 | 82 | 13 | 4 | ||
Demographic data | ||||||
Age (y) | 53.0 (17.5) | 60.0 (11.0) | 52.0 (14.0) | 55.0 (19.5) | 0.002 | 0.01 |
Sex, male (n) | 81 (71.7%) | 64 (78.0%) | 10 (76.9%) | 3 (75.0%) | 0.3 | 0.8 |
Height (cm) | 170.0 (14.0) | 168.0 (10.5) | 165.0 (15.0) | 166.5 (4.5) | 0.1 | 0.3 |
Weight (kg) | 67.0 (16.0) | 69.1 (15.6) | 66.0 (15.0) | 62.0 (17.0) | 0.6 | 0.2 |
BMI (kg/m2) | 24.2 (5.3) | 25.0 (5.7) | 22.9 (5.0) | 22.8 (5.6) | 0.09 | 0.09 |
Medical history | ||||||
Diabetes (n) | 2 (1.8%) | 3 (3.7%) | 1 (7.7%) | 0 (0.0%) | 0.3 | 0.6 |
Hypertension (n) | 36 (31.9%) | 39 (47.6%) | 4 (30.8%) | 0 (0.0%) | 0.08 | 0.05 |
Chronic obstructive pulmonary disease (n) | 3 (2.7%) | 5 (6.1%) | 1 (7.7%) | 0 (0.0%) | 0.2 | 0.6 |
Previous myocardial infarction (n) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.3 | 0.8 |
Peripheral vascular disease (n) | 9 (8.0%) | 6 (7.3%) | 1 (7.7%) | 0 (0.0%) | 0.8 | 0.9 |
Smoking (n) | 40 (35.4%) | 38 (46.3%) | 6 (46.2%) | 3 (75.0%) | 0.08 | 0.2 |
Preoperative laboratory tests | ||||||
Platelet (109/L) | 197.0 (57.5) | 183.0 (58.0) | 203.0 (54.5) | 137.5 (109.3) | 0.03 | 0.09 |
Preoperative renal function | ||||||
eGFR(mL/min/1.73 m2) | 99.8 (16.1) | 95.9 (18.1) | 101.7 (16.4) | 97.2 (37.6) | 0.04 | 0.02 |
Preoperative cardiovascular status | ||||||
Previous cardiovascular surgery (n) | 2 (1.8%) | 1 (1.2%) | 0 (0.0%) | 1 (25.0%) | 0.9 | 0.008 |
LVEF (%) | 58.0 (8.0) | 60.0 (4.5) | 52.5 (17.8) | 59.0 (11.8) | 0.2 | 0.08 |
Marfan syndrome (n) | 11 (9.7%) | 2 (2.4%) | 1 (7.7%) | 0 (0.0%) | 0.05 | 0.2 |
Intraoperative blood product use | ||||||
Erythrocytes (u) | 2.0 (3.0) | 2.0 (4.0) | 3.0 (3.0) | 4.0 (6.0) | 0.2 | 0.07 |
Fresh frozen plasma (ml) | 400.0 (0.0) | 400.0 (0.0) | 400.0 (300.0) | 650.0 (450.0) | 0.2 | 0.02 |
Platelets (u) | 1.0 (1.0) | 1.0 (1.0) | 1.0 (1.0) | 2.0 (0.8) | 0.5 | 0.004 |
Surgical details | ||||||
Involving the aortic arch (n) | 29 (25.7%) | 31 (37.8%) | 3 (23.1%) | 2 (50.0%) | 0.09 | 0.2 |
Involving the descending aorta (n) | 0 (0.0%) | 1 (1.2%) | 0 (0.0%) | 1 (25.0%) | 0.1 | < 0.001 |
CPB duration(min) | 117.5 (43.0) | 131.0 (50.5) | 137.0 (52.5) | 187.5 (34.8) | 0.005 | 0.003 |
DHCA or MHCA (n) | 10 (8.8%) | 11 (13.4%) | 0 (0.0%) | 2 (50.0%) | 0.3 | 0.03 |
Aortic cross-clamp time (min) | 81.0 (27.8) | 83.0 (31.3) | 94.0 (32.5) | 122.0 (42.8) | 0.08 | 0.04 |
Operation time (h) | 5.0 (1.0) | 6.0 (1.5) | 7.0 (2.3) | 8.5 (2.5) | < 0.001 | < 0.001 |
Combined surgery | ||||||
CABG (n) | 8 (7.1%) | 11 (13.4%) | 2 (15.4%) | 1 (25.0%) | 0.09 | 0.3 |
Outcomes | ||||||
Renal replacement therapy (n) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (25.0%) | 0.3 | < 0.001 |
ICU length of stay (day) | 3.0 (1.0) | 3.0 (2.0) | 5.0 (5.0) | 4.0 (7.5) | < 0.001 | < 0.001 |
> 7 d (n) | 2 (1.8%) | 4 (4.9%) | 4 (30.8%) | 1 (25.0%) | 0.02 | < 0.001 |
Intubation time (h) | 13.0 (8.0) | 14.0 (9.0) | 20.0 (28.5) | 28.5 (28.5) | 0.03 | 0.001 |
> 5 d (n) | 0 (0.0%) | 1 (1.2%) | 1 (7.7%) | 0 (0.0%) | 0.1 | 0.06 |
In-hospital mortality (n) | 1 (0.9%) | 0 (0.0%) | 1 (7.7%) | 1 (25.0%) | 0.5 | < 0.001 |