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Table 1 Patient Demographic and Preoperative Characteristics

From: Safety and efficacy of transaxillary transcatheter aortic valve replacement using a current-generation balloon-expandable valve

Variable

TF (n = 100)

TAx (n = 24)

TT (n = 20)

p Value

p Value between groups

Age, years

80.5 ± 7.6

82.9 ± 8.8

81.3 ± 5.3

0.386

 

Male

48 (48)

10 (41.7)

9 (45)

0.846

 

Body mass index, kg/m2

28.8 ± 6.2

27.1 ± 6.2

25.8 ± 5.0

0.095

 

Body surface area, m2

1.9 ± 0.2

1.8 ± 0.2

1.8 ± 0.3

0.208

 

Hypertension

86 (86)

20 (83.3)

20 (100)

0.179

 

Diabetes

38 (38)

15 (62.5)

5 (25)

0.029

TF vs TAx, 0.029;

TAx vs TT, 0.012

Coronary artery disease

76 (76)

19 (79.2)

16 (80)

0.895

 

Chronic kidney disease

23 (23)

11 (45.8)

9 (45)

0.025

TF vs TAx, 0.024;

TF vs TT, 0.042

End-stage renal disease

2 (2)

1 (4.2)

3 (15)

0.029

TF vs TT, 0.032

Creatininea, mg/dL

1.3 ± 1.1

1.6 ± 0.9

1.6 ± 1.6

0.291

 

Chronic lung disease

23 (23)

14 (58.3)

8 (40)

0.002

TF vs TAx, 0.001

Cerebrovascular accident

11 (11)

5 (20.8)

5 (25)

0.171

 

Previous cardiac surgery

17 (17)

5 (20.8)

7 (35)

0.186

 

Previous CABG

16 (16)

4 (16.7)

7 (35)

0.133

 

Previous PCI

19 (19)

11 (45.8)

7 (35)

0.015

TF vs TAx, 0.006

Permanent pacemaker

11 (11)

0 (0)

0 (0)

0.073

 

Atrial fibrillation

35 (35)

6 (25.0)

5 (25)

0.495

 

NYHA III/IV

90 (90)

22 (91.7)

18 (90)

0.969

 

STS-PROM

7.3 ± 5.2

11.3 ± 7.6

11.9 ± 11.8

0.005

TF vs TAx, 0.042;

TF vs TT, 0.026

Echocardiographic data

 Aortic valve area, cm2

0.7 ± 0.2

0.8 ± 0.1

0.7 ± 0.2

0.354

 

 Peak gradient, mmHg

68.9 ± 23.4

60.6 ± 19.4

66.7 ± 20.4

0.259

 

 Mean gradient, mmHg

39.2 ± 13.9

35.5 ± 11.6

39.7 ± 14.0

0.378

 

 Peak velocity, m/s

4.1 ± 0.7

3.8 ± 0.6

4.0 ± 0.7

0.229

 

 LVEF, %

54.8 ± 11.6

53.0 ± 11.1

49.0 ± 15.4

0.142

 

 PASP> 40 mmHg

14 (14)

11 (45.8)

6 (30)

0.002

TF vs TAx, 0.001

  1. a Creatinine level is the most recent value before surgery
  2. Values are mean ± SD or n (%)
  3. CABG coronary artery bypass graft, PCI percutaneous coronary intervention, LVEF left ventricular ejection fraction, NYHA New York Heart Association classification, PASP pulmonary artery systolic pressure, STS-PROM Society of Thoracic Surgeons predicted risk of mortality score, TAx transaxillary, TF transfemoral, TT transthoracic