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Table 1 In vivo effects of Sfrp1 on cardiac function of aged mice with acute MI

From: Sfrp1 protects against acute myocardial ischemia (AMI) injury in aged mice by inhibiting the Wnt/β-catenin signaling pathway

 

Control

M3

M3 + Sfrp1

M7

M7 + Sfrp1

LVEDd (mm)

3.32 ± 0.28

4.37 ± 0.31**

3.65 ± 0.29#

5.37 ± 0.53**

4.42 ± 0.35**&&

Pwdth (mm)

0.78 ± 0.05

0.52 ± 0.06**

0.71 ± 0.04##

0.46 ± 0.09**

0.66 ± 0.05*&&

FS (%)

49.84 ± 4.63

23.56 ± 2.32**

30.12 ± 3.67**#

14.45 ± 2.64**

33.26 ± 3.49**&&

  1. *P < 0.05, **P < 0.01, compared to control group; #P < 0.05, ##P < 0.01, compared to NC group or M3 group; &&P < 0.01, compared to M7 group
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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