Fig. 9From: Mechanical stretching of the pulmonary vein mediates pulmonary hypertension due to left heart disease by regulating SAC/MAPK pathway and the expression of IL-6 and TNF-αa. The protein expression levels of ERK1/2 in the pulmonary vein of sham and PH-LHD model rats were assessed by western blotting analysis. *P < 0.05 vs. S1, #P < 0.05 vs the M1. b PH-LHD model rats were treated with SB203580, SP600125, U0126 and streptomycin. *P < 0.05 vs. M2Back to article page