Survival risk prediction model for patients with pT1–3 N0M0 esophageal squamous cell carcinoma after R0 esophagectomy with two-field lymphadenectomy for therapeutic purposes

Table 4 Factors associated with DFS, RFS and LRFS according to multivariate Cox analysis

Factors	Groups	DFS		RFS		LRFS
Factors	Groups	HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)	p
Site of lesion	Upper	2.214 (1.409–3.479)	0.001	2.560 (1.552–4.222)	< 0.001	2.251 (1.295–3.911)	0.004
	Middle	1.384 (0.972–1.970)	0.071	1.551 (1.040–2.314)	0.031	1.434 (0.930–2.211)	0.103
	Lower	1.000		1.000		1.000
SLNs in CT	No	1.000		1.000		1.000
SLNs in CT	Yes	1.555 (1.187–2.036)	0.001	1.580 (1.185–2.106)	0.002	1.577 (1.145–2.174)	0.005
pT	pT₁	1.000		1.000		1.000
	pT₂	1.944 (1.306–2.891)	0.001	1.861 (1.222–2.834)	0.004	1.954 (1.204–3.171)	0.007
	pT₃	2.268 (1.583–3.249)	< 0.001	2.102 (1.433–3.082)	< 0.001	2.316 (1.491–3.600)	< 0.001

Abbreviations and definitions: DFS disease-free survival, RFS recurrence-free survival, LRFS locoregional recurrence-free survival, HR hazard ratio, CI confidence interval, SLNs in CT small lymph nodes in mediastinum (diameter < 1 cm) in CT image prior to surgery

ISSN: 1749-8090