Blood volume and hemoglobin mass in long-term heart transplant recipients with and without Anemia

Seiler, Florian; Ahlgrim, Christoph; Birkner, Philipp; Wrobel, Nina; Rilinger, Jonathan; Grundmann, Sebastian; Bode, Christoph; Pottgiesser, Torben

doi:10.1186/s13019-021-01510-1

Journal of Cardiothoracic Surgery

Table 2 Blood volume data and selected laboratory data of heart transplant recipients and healthy control subjects

From: Blood volume and hemoglobin mass in long-term heart transplant recipients with and without Anemia

	All subjects					Men					Women
	HTX	N	CON	N	p	HTX	N	CON	N	p	HTX	N	CON	N	p
Absolute
Hbmass (g)	785 ± 221	36	806 ± 121	46	0.597	843 ± 195	29	832 ± 100	41	0.781	543 ± 149	7	597 ± 59	5	0.409
RCV (ml)	2341 ± 653	36	2351 ± 345	46	0.938	2500 ± 572	29	2425 ± 280	41	0.517	1684 ± 579	7	1743 ± 189	5	0.809
PV (ml)	3871 ± 846	36	3649 ± 513	46	0.171	4012 ± 703	29	3757 ± 430	41	0.090	3289 ± 1175	7	2767 ± 156	5	0.289
BV (ml)	6212 ± 1433	36	6000 ± 801	46	0.428	6512 ± 1198	29	6182 ± 636	41	0.183	4973 ± 1750	7	4510 ± 230	5	0.514
BSA-corrected
Hb mass (g/m2)	386 ± 85	36	400 ± 45	46	0.387	407 ± 80	29	410 ± 35	41	0.873	299 ± 25	7	317 ± 23	5	0.222
RCV (ml/m2)	1152 ± 243	36	1165 ± 125	46	0.758	1208 ± 231	29	1195 ± 94	41	0.776	919 ± 132	7	924 ± 72	5	0.932
PV (ml/m2)	1919 ± 208	36	1814 ± 222	46	0.089	1948 ± 304	29	1855 ± 195	41	0.155	1798 ± 317	7	1472 ± 114	5	0.037
BV (ml/m2)	3071 ± 505	36	2979 ± 312	46	0.344	3156 ± 488	29	3050 ± 246	41	0.289	2717 ± 443	7	2396 ± 114	5	0.110
Calculated normal (ICSH)
RCV (ml)	2097 ± 369	36	2123 ± 250	46	0.713	2232 ± 232	29	2186 ± 181	41	0.376	1537 ± 301	7	1609 ± 81	5	0.563
PV (ml)	3104 ± 422	36	3135 ± 258	46	0.696	3246 ± 246	29	3197 ± 192	41	0.376	2515 ± 504	7	2627 ± 128	5	0.560
BV (ml)	5201 ± 788	36	5258 ± 508	46	0.703	5478 ± 478	29	5383 ± 373	41	0.376	4052 ± 805	7	4236 ± 209	5	0.560
Additional data
[Hb] (g/dl)	13.8 ± 1.6	36	14.8 ± 0.9	46	0.002	14.1 ± 1.5	29	14.8 ± 0.9	41	0.043	12.2 ± 1.2	7	14.5 ± 1.1	5	0.006
Hct (%)	41.0 ± 4.0	36	43.1 ± 2.7	46	0.012	41.9 ± 3.9	29	43.1 ± 2.7	41	0.161	37.3 ± 1.6	7	42.4 ± 3.2	5	0.020
Iron (μg/dl)	74 ± 28	33	–		–	75 ± 25	27	–		–	69 ± 40	6	–		–
Ferritin (ng/ml)	138 ± 139	31	–		–	144 ± 146	25	–		–	113 ± 110	6	–		–
Transferrin saturation (%)	20 ± 7	33	–		–	21 ± 7	27	–		–	18 ± 7	6	–		–

Footnote: Data presented mean ± SD. HTX = heart transplant recipients. CON = control subjects. BSA = body surface area. Hbmass = total hemoglobin mass. RCV = red cell volume. PV = plasma volume. BV = blood volume. *calculated normal values according to ICSH formulae (sex-dependent). [Hb] = venous hemoglobin concentration. Hct = venous hematocrit. N indicates the number of patients/subjects for whom data was available. p indicates the p-value (bold numbers indicate statistical significance)

Back to article page

ISSN: 1749-8090

Contact us

General enquiries: journalsubmissions@springernature.com