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Table 4 EGFR mutation in 95 tumors of 28 patients with MPLA

From: Surgical outcomes of one-stage resection for synchronous multiple primary lung adenocarcinomas with no less than three lesions

Variables

Total(n)

AIS

MIA

IA

P value

pGGO

mGGO

SN

P value

Wild

44

19

14

11

 

25

12

7

 

Mutation

51

8

3

40

0.000

18

27

6

0.039

L858R

29

7

1

21

 

7

18

4

 

19DEL

16

1

0

15

 

8

6

2

 

L858R/Othera

2

0

0

2

 

0

2

0

 

19DEL/Othera

1

0

1

0

 

1

0

0

 

Othera

3

0

1

2

0.057

2

1

0

0.372

  1. AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; IA, invasive adenocarcinoma; SN, solid nodule; pGGO, pure ground-glass opacity; mGGO, mixed ground-glass opacity; aRefers to other rare mutations including L861Q, G719X, 20Ins and T790M