Table 2 Intra- and postoperative characteristics
No anticoagulation (n = 104) | Warfarin or NOAC (n = 52) | p value | |
|---|---|---|---|
Proximal surgery | < 0.01 | ||
Supracoronary graft | 85 (85%) | 19 (34%) | |
Bentall procedure | 9 (9%) | 33 (59%) | |
Mechanical | 0 | 28 (54%) | |
Bioprosthesis | 9 (9%) | 5 (9%) | |
David/Yacoub | 4 (4%) | 0 | |
AVR and supracoronary graft | 2 (2%) | 4 (7%) | |
Distal surgery | 0.55 | ||
Ascending aortic graft | 77 (77%) | 46 (82%) | |
Hemiarch | 15 (15%) | 5 (9%) | |
Arch | 8 (8%) | 5 (9%) | |
Crossclamp | 5 (5%) | 3 (5%) | 1 |
Circulatory arrest | 50 (48%) | 29(56%) | 0.07 |
Retrograde cerebral perfusion | 42 (40%) | 19 (37%) | |
Antegrade cerebral perfusion | 11(11%) | 1(2%) | |
Primary tear excised | 62 (62%) | 36 (66%) | 0.67 |
GRF Glue | 65 (65%) | 29 (52%) | 0.11 |
CPB time (min) | 192 ± 54 | 218 ± 60 | 0.28 |
HCA time (min) | 24 ± 10 | 23 ± 10 | 0.39 |
Arterial cannulation | 0.11 | ||
Femoral | 75 (75%) | 50 (89%) | |
Subclavia | 3 (3%) | 2 (4%) | |
Ascending aorta or arch | 19 (19%) | 4 (7%) | |
Left ventricle | 3 (3%) | 0 | |
Reop bleeding | 11 (11%) | 1 (2%) | 0.06 |
Plasma (units) | 4.5 ± 4.4 | 3.7 ± 4.3 | 0.32 |
Platelets (units) | 3.6 ± 2.8 | 3.5 ± 2.2 | 0.97 |
Red blood cells (units) | 5.5 ± 5.1 | 4.1 ± 3.9 | 0.07 |
Fibrinogena (g) | 5.2 ± 3.4 | 5.0 ± 2.6 | 0.79 |
Recombinant FVII (mg) | 1.8 ± 2.4 | 1.8 ± 3.0 | 0.98 |
Recombinant FVII | 23 (39%) | 11 (30%) | 0.39 |
Bleeding 24 h (ml) | 860 ± 660 | 702 ± 306 | 0.17 |
Massive bleedingb | 23 (23%) | 6 (11%) | 0.06 |