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Table 1 Baseline characteristics of included patients

From: Risk factors analysis of hyperbilirubinemia after off-pump coronary artery bypass grafting: a retrospective observational study

Variablesa

All patients (n = 416)

Normal serum total bilirubin group (n = 384)

Hyperbilirubinemia group (n = 32)

Z/t /χ2

P value

Age ≥ 75 years

52(12.5)

49(12.8)

3(9.4)

0.310

0.783

Male

314(75.48)

284(73.96)

30(93.75)

6.252

0.012c

BMI, kg/m2

25.45 ± 3.21

25.45 ± 3.22

25.49 ± 3.04

0.073

0.942

Smoking history

217(52.16)

200(52.08)

17(53.13)

0.013

0.910

Comorbidities

     

Diabetes

186(44.71)

175(45.57)

11(34.28)

1.498

0.221

Hypertension

289(69.47)

268(69.79)

21(65.63)

0.242

0.623

Hyperlipidemia

235(56.49)

215(55.99)

20(62.5)

0.509

0.475

CKD

4(0.96)

4(1.04)

0(0.00)

0.337

1.000

COPD

8(1.92)

7(1.82)

1(3.13)

0.266

0.476

Peripheral vascular disease

32(7.69)

30(7.81)

2(6.25)

0.102

1.000

Cerebrovascular disease

92(22.12)

82(21.35)

10(31.25)

1.679

0.195

Anemia

147(35.34)

139(36.20)

8(25.00)

1.621

0.203

NYHA III–IV

74(17.79)

66(17.19)

8(25.00)

1.233

0.267

Myocardial infarction occurring > 21 days before operation

191(45.91)

178(46.35)

13(40.63)

0.390

0.532

Left ventricular ejection fraction, %

60.71 ± 11.01

60.77 ± 10.93

60.03 ± 12.07

0.364

0.716

Left ventricular end diastolic diameter, cm

49.48 ± 5.81

49.42 ± 5.74

50.23 ± 6.70

0.762

0.446

Left atrial diameter, cm

37.44 ± 4.55

37.41 ± 4.55

37.78 ± 4.63

0.439

0.661

Pulmonary artery hypertension

8(1.92)

6(1.56)

2(6.25)

3.441

0.120

Absolute value of red blood cell, × 1012/L

4.31 ± 0.54

4.30 ± 0.54

4.45 ± 0.50

1.542

0.124

Albumin, g/L

39.72 ± 3.41

39.71 ± 3.38

39.87 ± 3.78

0.036

0.971

Serum creatinine, μmol/Lb

73.70 (63.10, 87.25)

73.55 (62.60, 87.08)

76.75 (66.75, 88.30)

1.096

0.273

AST, U/Lb

22.00 (17.00, 31.00)

22.00 (17.00, 30.00)

21.00 (17.25, 36.00)

0.036

0.971

ALT, U/Lb

22.00 (16.00, 37.75)

22.00 (16.00, 30.00)

21.00 (14.25, 44.00)

0.361

0.718

ALP, U/Lb

69.00 (57.00, 80.00)

68.50 (57.00, 79.00)

74.50 (56.25, 86.25)

1.342

0.180

GGT, U/Lb

26.00 (18.00, 43.00)

26.00 (18.00, 41.00)

27.00 (19.25, 59.75)

1.513

0.130

Serum total bilirubin, μmol/L

12.41 ± 5.10

11.92 ± 4.52

18.28 ± 7.57

5.155

 < 0.001c

Operation time, hours

3.89 ± 0.71

3.87 ± 0.71

4.01 ± 0.76

0.581

0.561

Intraoperative blood loss, ml

465.79 ± 176.90

463.33 ± 174.40

495.31 ± 205.32

0.522

0.601

Perioperative blood transfusion [14]

162(38.94)

144(37.50)

18(56.25)

4.367

0.037c

Perioperative IABP implantation

101(24.28)

87(22.66)

14(43.75)

7.149

0.008c

Target vesselsb

3.00(2.00, 3.00)

3.00(2.00, 3.00)

3.00(2.00, 3.00)

0.343

0.732

  1. BMI body mass index, CKD chronic kidney disease, COPD chronic obstructive pulmonary disease, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, GGT γ-Glutamyl transpeptidase, IABP intra-aortic balloon pump
  2. aContinuous variables with normal distribution are presented as mean ± SD unless noted. bContinuous variables of non-normal distribution are presented as median (P25, P75). cP  < 0.05 was considered as statistically significant