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Table 2 Predictors of long-term Mortality: Final step of multivariable cox proportional stepwise regression analysis

From: Significance of preoperative left ventricular ejection fraction in 5-year outcome after isolated CABG

All-cause mortality

Variable

Multivariate HR [95% CI]

P value

EF ≥ 50%

Age * (years)

1.047 [1.038, 1.056]

 < 0.001

Diabetes mellitus

1.519 [1.336, 1.727]

0.001

Hypertension

1.502 [1.281, 1.762]

 < 0.001

eGFR < 60 (ml/min)

1.390 [1.099 – 1.759]

0.006

Dyslipidemia

0.783 [0.687, 0.893]

0.001

CVA

1.467 [1.130, 1.904]

0.004

PVD

1.687 [1.215, 2.342]

0.002

Carotid stenosis > 70%

2.365 [1.472, 3.799]

 < 0.001

50% < EF ≤ 35%

Age* (years)

1.031 [1.023, 1.038]

 < 0.001

Anemia

1.323 [1.123, 1.480]

0.001

Positive family history

0.857 [0.759, 0.967]

0.012

Diabetes mellitus

1.429 [1.275, 1.602]

 < 0.001

Hypertension

1.372 [1.195, 1.660]

 < 0.001

eGFR < 60 (ml/min)

1.993 [1.663, 2.388]

 < 0.001

Dyslipidemia

0.887 [0.791, 0.995]

0.041

LM stenosis > 50%

1.289 [1.123, 1.588]

0.015

CVA

1.759 [1.468, 2.108]

 < 0.001

COPD

2.020 [1.606, 2.542]

 < 0.001

Off-pump surgery

0.697 [0.564, 0.861]

0.001

PVD

1.477 [1.100, 1.981]

0.009

Carotid stenosis > 70%

1.957 [1.285, 2.979]

0.002

EF < 35%

eGFR < 60 (m/min)

1.825 1.399, 2.381]

 < 0.001

COPD

1.436 [1.027, 2.007]

0.034

Graft number

0.889 [0.807, 0.978]

0.016

  1. *HR estimated for increasing 1 year of age
  2. reference: eGFR > 90
  3. HR estimated for increasing 1 graft