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Table 2 Efficacy of sedation protocols in both groups

From: Comparison of the efficacy and safety of sedation protocols with the use of dexmedetomidine–remifentanil and propofol–remifentanil during percutaneous closure of atrial septal defects: a randomized clinical trial

 

D–R group (n = 29)

P–R group (n = 30)

Difference (95% CI)

P value

Induction time (min)

17.66 ± 2.65

11.43 ± 1.48

6.22 (5.10 to 7.35)

 < 0.001

Procedure duration (min)

52.48 ± 9.11

52.23 ± 7.41

0.25 (− 4.07 to 4.57)

0.908

Sedation duration (min)

70.14 ± 9.62

63.67 ± 7.02

6.47 (2.09 to 10.85)

0.004

Remifentanil infusion rate (μg/kg/h)

3.99 ± 0.08

3.97 ± 0.09

0.02 (− 0.03 to 0.06)

0.481

Maximum pain level (VAS)

  

0.786

 0 (no pain)

24 (82.8%)

24 (80.0%)

  

 < 3 (mild pain)

5 (17.2%)

6 (20.0%)

  

Recovery time (min)

13.03 ± 1.82

12.20 ± 2.17

0.83 (− 0.21 to 1.88)

0.116

Additional propofol required

    

 Patients, n (%)

4 (13.8%)

2 (6.7%)

7.1% (− 8.3 to 22.5%)

0.424

 Dose (mg)

17.50 ± 5.00

15.00 ± 7.07

2.50 (− 10.94 to 15.94)

0.633

Surgeon satisfaction score

  

0.006

 1 (very satisfied)

11 (37.9%)

22 (73.3%)

  

 2 (satisfied)

12 (41.4%)

6 (20.0%)

  

 3 (neutral)

6 (20.7%)

2 (6.7%)

  

Patient satisfaction score

  

0.668

 1 (very satisfied)

23 (79.3%)

22 (73.3%)

  

 2 (satisfied)

4 (13.8%)

7 (23.3%)

  

 3 (neutral)

2 (6.9%)

1 (3.3%)

  
  1. D–R group: dexmedetomidine–remifentanil group; P–R group: propofol–remifentanil group; VAS: visual analog scale