Risk factors for postoperative delirium on oxygen delivery-guided perfusion

Table 3 The two primary DO₂ components during CPB and delirium

Variable	No delirium (n = 53)	Subsyndromal delirium (n = 163)	Clinical delirium (n = 9)	P value
Variable	No delirium (n = 53)	Subsyndromal delirium (n = 163)	Clinical delirium (n = 9)	Overall	ND vs. SD	ND vs. CD	SD vs. CD
AUC < Hct²¹	0 (0–0)	0 (0–0)	0 (0–6.5)	0.268
Time < Hct²¹ (min)	0 (0–0)	0 (0–0)	0 (0–2.2)	0.308
AUC < Hct²³	0 (0–33.5)	6 (0–60)	35 (10.5–122)	0.055
Time < Hct²³ (min)	0 (0–8.2)	2 (0–16)	9.3 (2.7–20.9)	0.049	0.096	0.117	0.540
AUC < Hct²⁵	60 (17.5–221.5)	154 (22–421)	205 (94.5–562.5)	0.048	0.084	0.153	0.587
Time < Hct²⁵ (min)	18.3 (5.5–43.9)	31.7 (7–75.3)	58 (23.3–125.7)	0.021	0.081	0.055	0.271
AUC < PI^2.6	0.79 (0.26–3.88)	0.44 (0.04–2.50)	0.12 (0.02–2.90)	0.223
Time < PI^2.6 (min)	3.3 (1.7–26.8)	3 (0.7–11.0)	5 (0.9–10.2)	0.344
AUC < PI^2.7	8.6 (2.3–22.4)	3.8 (1.3–14.3)	4.0 (2.0–20.4)	0.097
Time < PI^2.7 (min)	41 (14.2–99)	20.3 (7.3–66)	15.3 (8.8–80.9)	0.086
AUC < PI^2.8	30.6 (13.3–61)	16.1 (6.5–42.1)	10.8 (5.7–48.2)	0.081
Time < PI^2.8 (min)	91 (42.3–132.5)	62.7 (21.7–116)	44.7 (14.7–134)	0.065

AUC < Hct²¹, area under the curve below the 21% hematocrit thresholds; AUC < Hct²³, area under the curve below the 23% hematocrit thresholds; AUC < Hct²⁵, area under the curve below the 25% hematocrit thresholds; AUC < PI^2.6, area under the curve below the 2.6 perfusion index thresholds; AUC < PI^2.7, area under the curve below the 2.7 perfusion index thresholds; AUC < PI^2.8, area under the curve below the 2.8 perfusion index thresholds; CD, clinical delirium; CPB, cardiopulmonary bypass; DO₂, oxygen delivery; Hct, hematocrit; ND, no delirium; SD, subsyndromal delirium; Time < Hct²¹, cumulative time below the 21% hematocrit thresholds; Time < Hct²³, cumulative time below the 23% hematocrit thresholds; Time < Hct²⁵, cumulative time below the 25% hematocrit thresholds; Time < PI^2.6, cumulative time below the 2.7 perfusion index thresholds; Time < PI^2.8, cumulative time below the 2.8 perfusion index thresholds; Time < PI^2.8, cumulative time below the 2.8 perfusion index thresholds

ISSN: 1749-8090