Fig. 5

Nesfatin-1 attenuated inflammatory response in LPS-stimulated RAW 264.7 cells. Cells were treated with LPS (1 μg/mL) in the presence and absence of Nesfatin-1 (50, 100 nM). (A) The mRNA levels of IL-6, IL-1β, and TNF-α; (B) Protein levelsof IL-6, IL-1β and TNF-α (***P < 0.0001 vs. vehicle group; #, ##, P < 0.01, 0.001 vs. LPS treatment group)