Predictors of major adverse events and complications after ventricular septal defects surgical closure in children less than 10 kg

Table 6 Univariate analysis and multivariable regression analysis for the factors associated with a prolonged hospital stay

Prolonged hospital stay
Univariate analysis						p value
Sex	Female	54	55.7	6	20.0	0.001*
Sex	Male	43	44.3	24	80.0	0.001*
Age at operation	Median (IQR)	8.0 (6.0–10.0)		9.0 (7.013.0)		0.086
Weight at operation	Median (IQR)	5.5 (4.7–6.8)		6.0 (5.0–8.0)		0.297
Down Syndrome	No	70	72.2	18	60.0	0.207
Down Syndrome	Yes	27	27.8	12	40.0	0.207
Type of VSD	Others	11	11.3	5	16.7	0.806
	Inlet	34	35.1	10	33.3
	Outlet	22	22.7	8	26.7
	PM	25	25.8	5	16.7
	Multiple	5	5.2	2	6.7
Associated CHD	No	44	45.4	8	26.7	0.069
Associated CHD	Yes	53	54.6	22	73.3	0.069
Right ventricular hypertrophy	No	86	88.7	15	50.0	< 0.001*
Right ventricular hypertrophy	Yes	11	11.3	15	50.0	< 0.001*
Pulmonary artery banding	No	87	89.7	14	46.7	< 0.001*
Pulmonary artery banding	Yes	10	10.3	16	53.3	< 0.001*
VSD Repair	Interrupted	50	51.5	21	70.0	0.075
VSD Repair	Continuous	47	48.5	9	30.0	0.075
Significant intraoperative Residual VSD	No	93	95.9	20	66.7	< 0.001*
Significant intraoperative Residual VSD	Yes	4	4.1	10	33.3	< 0.001*
Cross clamp time (Minutes)	Median (IQR)	58.0 (49.0–67.0)		73.5 (54.0–90.0)		0.004*
Total CPB time (Minutes)	Median (IQR)	83.0 (70.0–92.0)		110.0 (83–143)		< 0.001*

Multivariable logistic regression analysis
Risk factors	Beta coefficient	p value	Odds ratio	95% CI Odds ratio
Sex (male)	2.552	0.001*	12.8281	2.990–55.030
Pulmonary artery banding	2.542	< 0.001*	2.669	3.790–42.544
Significant intraoperative (3 mm) residual VSD	2.973	< 0.001*	19.551	3.809–100.358

IQR interquartile range, VSD ventricular septal defect, CHD congenital heart disease, CPB cardiopulmonary bypass;
^*significant at p < 0.05

ISSN: 1749-8090