From: Sufentanil: a risk factor for lactic acidosis in patients after heart valve surgery
Variable | Sufentanil infusion rates < 1.88 µg. kg-1. h-1 group(n = 51) | Sufentanil infusion rates > 1.88 µg. kg-1. h-1 group(n = 51) | P value |
---|---|---|---|
Female sex | 25 (49.1) | 16 (31.3) | 0.43 |
Age (years) | 54.29 ± 8.77 | 55.29 ± 13.75 | 0.66 |
Body surface area (m2) | 1.71 ± 0.21 | 1.73 ± 0.16 | 0.47 |
Preoperative diabetes mellitus | 7(13.7) | 3 (5.8) | 0.96 |
Preoperative atrial fibrillation | 14 (27.4) | 8 (15.6) | 0.64 |
Preoperative hypertension | 17 (33.3) | 10 (19.6) | 0.25 |
Preoperative EF value (%) | 61 (58, 65) | 62 (56, 68) | 0.31 |
Preoperative left ventricle (end-diastolic diameter, cm) | 51 (48, 54) | 52 (48, 55) | 0.09 |
Cardiopulmonary bypass time (min) | 125.29 ± 49.47 | 122.27 ± 60.64 | 0.78 |
Aortic occlusion time (min) | 94.39 ± 42.46 | 91.56 ± 51.73 | 0.76 |
Total operation time (min) | 260 (210, 300) | 225 (180, 300) | 0.22 |
Total sufentanil dosage (ug) | 420.58 ± 120.24 | 590.19 ± 146.29 |  < 0.001 |
Relative sufentanil infusion rate (µg kg−1 h−1) | 1.41 ± 0.26 | 2.44 ± 0.44 |  < 0.001 |
8Â h mean blood glucose level (mmol/L) | 10.5 (8.6,12.1) | 9.8 (8.6,11.2) | 0.4 |
Infusion rate of propofol (mg/kg h) | 6.9 (6.5,7.5) | 7 (6.5,8) | 0.45 |
8Â h Total dopamine dosage (mg) | 165.6 (115.2,196.8) | 158.4 (141.6, 175.2) | 0.4 |
8Â h Total Epinephrine dosage (mg) | 9 (17.6) | 13 (25.4) | 0.36 |