Characteristics and prognosis of primary pulmonary osteosarcoma: a pooled analysis

Table 2 Univariable analysis of overall survival and cancer-specific survival in all patients and patients without metastasis

Characteristics	All patients^a		Patients without metastasis^a
Characteristics	OS P value	CSS P value	OS P value	CSS P value
Demographics
Age	0.099	0.188	0.316	0.656
Sex	0.432	0.442	0.818	0.805
Tumor characteristics
Laterality^b	0.324	0.384	0.194	0.260
Location (UL, ML or LL)^c	0.406	0.728	0.219	0.445
Location (central or peripheral)^d	0.433	0.664	0.368	0.539
Size^e	0.009	0.023	0.043	0.108
Recorded in situ tumor(s)^f	0.572	0.352	0.688	0.463
Metastasis	0.017	0.002	–	–
Imaging manifestations
Pleural effusion on X-ray/CT	0.016	0.017	0.014	0.025
Calcification found in pulmonary mass on CT	0.048	0.034	0.033	0.012
Intensive uptake on bone scintigraphy	0.999	0.926	0.886	0.701
Microscopic findings
Osteocyte	0.739	0.884	0.240	0.234
Osteoid	0.152	0.491	0.278	0.915
Chondrocyte^g	0.922	0.910	0.886	0.929
Treatment
Surgery	< 0.001	< 0.001	< 0.001	< 0.001
Chemotherapy	0.343	0.682	0.601	0.859
Radiotherapy	0.642	0.896	0.266	0.596

OS overall survival, CSS cancer-specific survival, UL upper lobe, ML middle lobe, LL lower lobe, CT computed tomography
^aPatients with unknown survival status or time were excluded for analysis
^bThe cases with uncertain laterality were classified as the left lung
^cThe cases with an uncertain lobe location were classified as the upper lobe of the lung
^dThe cases with uncertain location (central or peripheral) were classified as a peripheral site of the lung
^eThe cases with an uncertain tumor size were classified as lower than 7 cm
^fThe cases with an uncertain number with recorded in situ tumor(s) were classified as single in situ tumor
^gChondrocyte was referred to as chondrocyte, chondroblast, or chondroid

ISSN: 1749-8090