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Table 2 ECMO treatment and outcome of the 5 cases

From: Five critically ill pregnant women/parturients treated with extracorporeal membrane oxygenation

Case

Conventional rescue time (h)

ECMO type

Duration of ECMO (d)

Duration of intensive care (d)

Hospital stays (d)

Other treatment

Transfusion of blood and blood products

Complications

Maternal and neonatal outcomes

Case 1

4

VA

16

25

139

VAV, atrial septal defect repair, double lung transplantation, tracheotomy

SLRRBC (14 U), plasma (2500 ml), platelet (1 dose)

Thrombus at the MO, local stratification and plasma penetration of the MO, pulmonary infection, inferior vena cava thrombosis

Mother died at 10 months after delivery and newborn survived

Case 2

7

VA → VV

22

22

22

Blood purification, VAV, anti-infection, acid suppression, nutritional support

SLRRBC (41 U), plasma (7550 ml), CCF (40 U), platelet (84 dose)

Ventilator-associated pneumonia, coagulopathy, multiple organ dysfunction syndrome, central diabetes insipidus, brain death, post-cardiopulmonary resuscitation syndrome, liver insufficiency, microbubbles in ECMO tubes

Mother died and newborn survived

Case 3

6

VV

2

18

65

VAV, continuous veno-venous hemofiltration (CVVH)

SLRRBC (40 U), plasma (4900 ml), CCF (10 U), platelet (2 dose)

Pulmonary infection, Sheehan's syndrome, hypopituitary crisis, acute hepatic and renal insufficiency, right lower limb ischemia, postpartum depression

Both mother and newborn survived

Case 4

4

VV

3

6

18

VAV

SLRRBC (3 U), plasma (400 ml)

Pulmonary infection

Both mother and newborn survived

Case 5

17

VA

1/2

39

44

VAV, hormone shock, immunoregulation, dehydration, tracheotomy, continuous renal replacement therapy (CRRT)

SLRRBC (18 U), plasma (5525 ml), platelet (9 dose)

Pulmonary infection, pulmonary edema, acute renal insufficiency, hypothyroidism, severe metabolic acidosis, pancreatitis, coagulopathy

Both mother and newborn died

  1. ECMO, extracorporeal membrane oxygenation; VAV, ventilator-assisted ventilation; SLRRBC, suspended leukocyte-reduced red blood cells; CCF, cryoprecipitate coagulation factor; MO, membrane oxygenation