Table 3 Hub proteins with significant centrality values, based on degree
No | Hub genes | Protein name | Degree |
|---|---|---|---|
1 | APOA1 | Apolipoprotein A-I | 41 |
2 | BGN | Biglycan | 24 |
3 | SPP2 | Secreted phosphoprotein 24 | 23 |
4 | ABCA1 | Phospholipid-transporting ATPase | 18 |
5 | APP | Amyloid-beta precursor protein | 15 |
6 | EAF1 | ELL-associated factor 1 | 15 |
7 | MCTP2 | Multiple C2 and transmembrane domain-containing protein 2 | 15 |
8 | TRIM41 | E3 ubiquitin-protein ligase TRIM41 | 14 |
9 | APOB | Apolipoprotein B-100 | 13 |
10 | BRAP | BRCA1-associated protein | 13 |
11 | SDCBP | Syntenin-1 | 12 |
12 | PCMT1 | Protein-L-isoaspartate(D-aspartate) O-methyltransferase | 11 |
13 | MIPOL1 | Mirror-image polydactyly gene 1 protein | 11 |
14 | TGFB1 | Transforming growth factor beta-1 proprotein | 10 |
15 | ACOXL | Isoform 3 of Acyl-coenzyme A oxidase-like protein | 10 |
16 | FBLN1 | Fibulin-1 | 10 |
17 | TRIM27 | Zinc finger protein RFP | 10 |
18 | CLEC4G | C-type lectin domain family 4 member G | 9 |
19 | PLTP | Phospholipid transfer protein | 9 |
20 | NAXE | NAD(P)H-hydrate epimerase | 9 |