Gender-related differences on outcome following transcatheter mitral valve repair (TMVR): a systematic review and meta-analysis

Table 2 Baseline comparability analysis results

Baseline	Studies	Data type	Effect measure	Model	Participants	Effect estimate	LCI	UCI	Q	P(Q)	Z	P(Z)
Age (Years)	7	Continuous	Mean Difference	Fixed	12,867	− 1.02	− 1.42	− 0.63	49.07	< 0.00001	5.08	< 0.00001
BMI	3	Continuous	Mean Difference	Fixed	1987	0.75	0.22	1.28	0.36	0.83	2.77	0.006
Logistic EuroSCORE	4	Continuous	Mean Difference	Fixed	1739	− 0.27	− 1.68	1.15	0.59	0.90	0.37	0.71
STS score	2	Continuous	Mean Difference	Fixed	999	0.94	0.06	1.82	1.76	0.18	2.09	0.04
NYHA ≥ III	5	Dichotomous	Odds Ratio	Fixed	2288	0.86	0.65	1.13	2.74	0.6	1.09	0.28
MR ≥ 3 grade	3	Dichotomous	Odds Ratio	Fixed	1330	2.11	0.88	5.04	1.09	0.58	1.67	0.09
Hypertension	7	Dichotomous	Odds Ratio	Fixed	27,408	1.03	0.98	1.09	3.70	0.72	1.34	0.18
Diabetes mellitus	7	Dichotomous	Odds Ratio	Fixed	27,529	1.17	1.10	1.25	19.47	0.003	4.73	< 0.00001
Prior PCI	5	Dichotomous	Odds Ratio	Fixed	26,215	1.67	1.56	1.79	2.53	0.64	14.95	< 0.00001
Prior CABG	5	Dichotomous	Odds Ratio	Fixed	26,843	2.92	2.74	3.11	2.78	0.6	33.70	< 0.00001
Prior stroke	6	Dichotomous	Odds Ratio	Fixed	12,312	1.07	0.95	1.19	10.18	0.07	1.12	0.26
Coronary Artery disease	5	Dichotomous	Odds Ratio	Fixed	26,898	2.03	1.94	2.14	13.50	0.009	27.89	< 0.00001
COPD	5	Dichotomous	Odds Ratio	Fixed	2292	1.23	1.00	1.52	9.14	0.06	1.95	0.05
Renal failure	4	Dichotomous	Odds Ratio	Fixed	16,594	1.73	1.62	1.84	11.75	0.008	16.7	< 0.00001
Atrial Fibrillation	5	Dichotomous	Odds Ratio	Fixed	2305	1.01	0.85	1.20	5.61	0.23	0.08	0.94
Previous MI	6	Dichotomous	Odds Ratio	Fixed	2823	2.00	1.67	2.39	11.37	0.04	7.49	< 0.00001

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