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Table 6 Uni- and multivariable analysis on neurological injury

From: S100B predicts neurological injury and 30-day mortality following surgery for acute type A aortic dissection: an observational cohort study

Outcome on neurological injury

Univariable analysis

Multivariable analysis

OR

CI 95%

p

OR

CI 95%

p

Diabetes Mellitus

1.89

1.10–3.24

0.02

2.48

1.25–4.91

< 0.01

Cerebral malperfusion

3.43

1.92–6.14

< 0.01

4.23

2.03–8.84

< 0.01

CPB time (per 1 min increment)

1.00

1.00–1.01

0.04

1.00

1.00–1.01

0.23

Proximal surgical technique

Supracoronary graft

  

0.27

  

0.16

Bentall procedure

0.63

0.34–1.17

0.14

0.42

0.19–0.93

0.03

Isolated aortic valve

1.56

0.64–3.84

0.33

1.03

0.33–3.21

0.96

Root replacement/Aortic valve repair replacement

0.49

0.06–4.13

0.51

0.38

0.04–3.84

0.41

S100B T2 (per 0,1 μg/l increment)

1.15

1.07–1.23

< 0.01

1.22

1.01–1.35

< 0.01

S100B T2 ≥ 0.23 μg/l

4.47

2.63–7.60

< 0.01

4.71

2.59–8.57

< 0.01

  1. CPB Cardiopulmonary bypass, T2 24 h postoperatively