Minimally invasive versus open esophagectomy after neoadjuvant therapy for esophageal cancer: a meta-analysis

Table 1 Specific characteristics of 6 studies

Study	Country	Study type	Histology	Adjuvant treatment	Surgical technique	N1	N2	OS
Study	Country	Study type	Histology	Adjuvant treatment	Surgical technique	N1	N2	HR	95% CI
Chen 2021	China	Single-center retrospective	SCC	NCRT/NCT	Mckeown	120	75	0.61	0.38–0.96
Chen 2022	China	Multi-center PSM	SCC	NCRT	Mckeown/Ivor Lewis	706	353	0.87	0.74–1.02
Hamai 2021	Japan	Single-center retrospective	SCC	NCRT/NCT	Mckeown	68	65	0.83	0.50–1.37
Merritt 2021	USA	Single-center PSM	SCC/AC	NCRT	Ivor Lewis	142	68	0.95	0.59–1.53
Tang 2018	China	Single-center retrospective	SCC	NCT	Mckeown/Ivor Lewis	42	57	1.35	0.35–5.17
Tapias 2016	USA	Single-center retrospective	SCC/AC	NCRT/NCT	Ivor Lewis	56	74	1.07	0.61–1.87

SCC squamous cell carcinoma, AC adenocarcinoma, NCRT neoadjuvant chemoradiotherapy, NCT neoadjuvant chemotherapy, PSM propensity score matching, OS overall survival, HR hazard ratio, CI confidence interval, N number

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