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Table 1 Details of cases in which transdermal patches of bisoprolol were used for postoperative atrial fibrillation

From: Managing postoperative atrial fibrillation after open-heart surgery using transdermal β1 blockers

Age range

(years)

Disease

Comorbidities

Operation

Type

Op time (min)

EF (pre-op)

Pre-op Cr

Patch applied (POD)

No. of pieces used

Medications

24 h sinus

Final ECG

Complication

80–89

MR, TR, PAF

HT, DL

MAP, TAP, PVI

256

68.9

0.6

4

1

 

+

Sinus

 

70–79

IHD

HT, DL, DM, obe.

OPCAB

227

61.6

1

1

1

  

Sinus

 

50–59

IHD

obe.

OPCAB

334

42.4

0.8

1

1

  

Sinus

 

60–69

MR, AF

HT, DL, obe.

MAP, MVP, maze

245

64.8

1.5

1

1

  

AF

DC

removal

80–89

VSP

HT, DL, DM

VSP repair

277

44.0

0.9

2

1

  

Sinus

Death

(2 POD)

80–89

ASR, IHD

HT

AVR, CABG

272

56.0

0.8

0

1

  

Sinus

 

70–79

MR, PAF

 

MVR, maze

324

60.4

1.1

7

1

 

+

Sinus

 

70–79

IHD

HT, DL, DM

MAP, CABG

393

38.7

1.5

2

1

  

Sinus

 

80–89

IHD

HT, DM, HD

AVR, CABG

273

64.9

8.5

8(2), 24

3

  

Sinus

 

70–79

DAA

HT

TAR

415

61.9

0.5

2, 5, 7

3

Verapamil

 

Sinus

 

70–79

AS

HT, DM

AVR

196

51.0

0.6

7, 8

2

  

Sinus

 

70–79

AS

DL

AVR

221

66.0

0.6

3

1

 

+

Sinus

 

70–79

AS, OMI

HT, DM, HD

AVR

244

38.3

8.5

8

1

 

+

Sinus

 

70–79

AR

HT

AVR (re-do)

333

59.4

1.31

3 (2)

2

Landiolol

+

Sinus

DC

80–89

MR, TR, PAF

 

MVP, MAP, TAP, maze

251

63.7

0.5

3

1

 

+

Sinus

 

70–79

AR, MR, TR, PAF

HT, DL, obe.

AVR, MAP, maze

288

39.4

3.8

3

1

  

Sinus

 

60–69

IHD

HT, DL, DM, obe

OPCAB

301

50.0

1.2

1

1

 

+

Sinus

 

50–59

TAA

HT

Desc. A repl.

562

36.5

0.7

2 (2), 3, 4

4

Landiolol

Digitalis

 

Sinus

DC

50–59

AAE, AR

HT, DL, obe.

Bentall

338

48.4

0.72

2

1

 

+

Sinus

 

80–89

IHD, MR

 

MAP, CABG

357

19.4

1.11

8

1

  

Sinus

Removal

80–89

AS

HT

AVR

198

60.4

0.78

2 (2)

2

Landiolol

Digitalis

Verapamil

 

Sinus

 

60–69

AS

HT, DL, DM

AVR

219

64.8

0.94

0

1

Landiolol

 

Sinus

 

50–59

MR, TR, AF

 

MAP, TAP, maze

281

35.9

0.82

0,7

2

  

AF

RR7→DOA

removal

70–79

AS, MR, AF

DL, obe.

AVR, MVP, maze

244

52.9

0.81

3

1

  

Sinus

DC

60–69

ASR, PAF

obe.

AVR, maze

239

34.7

1.51

10

1

Verapamil

 

Sinus

DC

60–69

IHD, AR

HT, DL, DM

AVR, CABG

377

27.4

1.04

3,4

2

Digitalis

+

Sinus

 

30–39

MR

 

MAP, MVP

243

66.3

0.82

3

1

 

+

Sinus

 

80–89

RV perforation

HT

CABG (emerg) RV repair

180

63.5

0.86

4,5

2

  

u/i

CI, death

(30 POD)

70–79

AR

 

AVR

231

39.1

1

1,2,4(2)

4

  

Sinus

 

60–69

IHD

HT, obe., HD

CABG

269

23.4

10.6

3,5,7

3

  

Sinus

 

90–99

ASR

HT, DL

AVR

240

61.5

1

2,7,9

3

  

AF

DC

80–89

AS

HT

AVR

197

63.0

1.44

1

1

  

Sinus

 

60–69

MR, TR

HT, obe., HD

MAP, MVP, TAP

210

57.8

0.47

8

1

Amiodaron

+

Sinus

 

80–89

IHD, AS

HT, DL, obe.

AVR, CABG

334

60.8

0.7

1

1

Amiodaron

+

Sinus

 

70–79

IHD, AS

HT, obe., HD

AVR, CABG

275

65.9

1

2,3,4,

5,6

5

  

Sinus

 

70–79

MR, TR, OMI

HT, DL

MAP, TAP, CABG, maze

334

34.0

1.4

5,8

2

  

Sinus

DC

60–69

MR, TR

HT, obe., HD

MVR, TAP

435

62.6

0.7

6,7,8,

10,13

5

Amiodaron

 

Sinus

Temp.

pacing

60–69

AR, MR, TR, AF

HT

AVR, MAP, TAP, maze

303

30.0

1.1

7

1

  

Sinus

DC

70–79

MR, TR

H, DM, obe.

MVR, TAP

354

61.5

0.8

3

1

  

Sinus

Death

(1 m)

80–89

IHD

HT, DL, DM

CABG

280

42.0

2.7

4

1

Landiolol

amiodaron

 

Sinus

 

70–79

AR, AAE

HT, DL

AVR, Asc Ao repl.

350

44.8

0.93

2,5,8

3

Amiodaron

 

Sinus

DC

60–69

MR, TR, AF

 

MVR, TAP, maze

246

48.9

0.75

0

1

  

Sinus

 

70–79

AR

HT

AVR (re-do)

333

59.4

1.31

2(2)

2

Landiolol

 

Sinus

DC

50–59

AS, Asc. AA

 

AVR, Asc Ao repl.

305

54.6

0.84

0

1

  

Sinus

DC

70–79

IHD

HT, DM, obe.

AVR, CABG, myectomy

297

62.3

0.7

2,6

2

  

Sinus

 

50–59

AAE, AR

HT, DL, obe.

Bentall

338

48.4

0.72

2

1

Landiolol

 

Sinus

 

70–79

TAAA

HT, DL, DM

TAAA repl.

408

58.3

1.39

2

1

Landiolol

 

Sinus

 

70–79

MR, TR, AF

 

MVR, TAP, maze

251

57.0

1.11

17,20

2

  

Sinus

DC

80–89

ASR

Obe

AVR

193

65.5

0.58

1

1

 

+

Sinus

 

70–79

AS

HT, DL

AVR

217

60.7

0.6

37

1

  

Sinus

 

80–89

AS

HT, DL

AVR

227

61.7

0.7

5

1

 

+

Sinus

 

80–89

AS

HT, DL

AVR

229

56.1

1.14

2,3,4,

6,11

5

  

Pacing

PM (SSS)

60–69

MSR, TR, AF

HT, DL, DM

MVR, TAP, maze

219

54.9

1.93

5

1

  

Sinus

DC

80–89

AS

obe.

AVR (re-do)

298

49.8

0.78

1, 5,7,

12

4

  

AF

 

70–79

AS

HT, DL, obe.

AVR

167

50.2

0.84

2

1

  

Sinus

 

70–79

MR, TR, IHD

HT, DL

MVP, MAP, TAP, CABG

311

57.7

1.27

1

1

 

+

Sinus

 

80–89

AS

HT

AVR

162

52.3

1.07

1,3

2

 

+

Sinus

 

60–69

MS, AS, TR

DL, obe.

DVR, maze

267

58.2

1.17

3(2),4

3

Digitalis

Amiodaron

 

Sinus

DC

60–69

TAA

HT

Total arch

426

63.4

0.99

1

1

 

+

Sinus

 

50–59

IHD, AR

HT, DL, obe.

AVR, CABG

361

58.5

0.99

8,9

2

Verapamil

 

Sinus

DC

60–69

AS

 

AVR

168

62.5

0.95

1

1

  

Sinus

 

70–79

lt subcl. AA

HT, DL, DM

Total arch, omen.

390

60.0

0.47

1,2

2

Digitalis

 

Sinus

 

70–79

AR, TR, PAF

 

AVR, TAP, PVI

228

45.8

0.84

10,17,18

3

Amiodaron

Digitalis

 

AF

 

90–99

AS, OMI

 

AVR

205

50.7

0.74

3

1

  

Sinus

 

70–79

MR, HOCM

HT, DL

MVR, myectomy

226

61.8

0.52

12

1

 

+

Sinus

 
  1. The mean operative time was 286.5 ± 75.8 (range, 162–562) min. The mean preoperative EF was 53.2 ± 11.6% (range, 19.4–68.9%). The average number of Bisono tape prescriptions during hospitalization was 1.8 ± 1.1 (range, 1–5). The median first prescription date was on POD 2 (range, POD 0–37)
  2. Abbreviations: AAE: aortic annular enlargement; AF: atrial fibrillation; AR: aortic valve regurgitation; AS: aortic valve stenosis; Asc, AA: ascending Asc. Ao: ASR: aortic stenosis and regurgitation; AVR: aortic valve replacement; CI: cerebral infarction; CABG: coronary artery bypass grafting; Cr: creatinine; DAA: dissecting aneurysm of the aorta; DM: diabetes mellitus; Desc. A: descending aorta; DC: direct current cardioversion; DL: dyslipidemia; DOA: dopamine; DVR: double valve replacement; ECG: electric cardiogram; EF: ejection fraction; emerg.: emergent; HR; heart rate; HT: hypertension: HOCM: hypertrophic obstructive cardiomyopathy: IHD: ischemic heart disease; MAP: mitral annulus plasty; MVP: mitral valve plasty; MR: mitral valve regurgitation; MVR: mitral valve replacement; MS: mitral valve stenosis; lt. subcl. AA: subclavian arterial aneurysm; Obe: obesity; OMI: old myocardial infarction; omen: omental packing; Op: operation; OPCAB: off-pump coronary artery bypass; PM: pacemaker; PAF: paroxysmal atrial fibrillation; POAF: postoperative atrial fibrillation; POD: postoperative day; repl.: replacement; PVI: pulmonary vein isolation; RR: RR interval; RV: right ventricle, SSS: sick sinus syndrome; TAA: thoracic aortic aneurysm; TAAA: thoracoabdominal aortic aneurysm; TAP: tricuspid annulus plasty; TAR: total arch replacement; Temp.: temporary; TR: tricuspid valve regurgitation; u/i: unidentified; VSP: ventricular septal perforation
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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