Table 1 Master protocol trials and corresponding objectives, according to Woodcock and LaVange, 2017 [1]
Trial type | Objective |
|---|---|
Umbrella | Multiple targeted therapies in the context of a single disease |
Basket | A single targeted therapy in the context of multiple diseases or disease subtypes |
Platform | Multiple targeted therapies in the context of a single disease in a perpetual manner, with therapies allowed to enter or leave the platform on the basis of a decision algorithm |