Table 1 The associations of clinicopathological characteristics between training cohort (SYSUCC) and external validation cohort (HNCH)
Variables | All patients (N = 996) | Training Cohort (SYSUCC, N = 819) | Validation Cohort (HNCH, N = 177) |
|---|---|---|---|
No. of patients/ mean ± std | |||
Sex | |||
Male | 680 (68.3%) | 577 (70.5%) | 103 (58.2%) |
Female | 316 (31.7%) | 242 (29.5%) | 74 (41.8%) |
Smoking history | |||
No | 416 (41.8%) | 318 (38.8%) | 98 (55.4%) |
Yes | 580 (58.2%) | 501 (51.2%) | 79 (44.6%) |
Drinking history | |||
No | 703 (70.6%) | 590 (72.0%) | 113 (63.8%) |
Yes | 293 (29.4%) | 229 (28.0%) | 64 (36.2%) |
Tumor differentiation | |||
Grade I | 300 (30.1%) | 226 (27.6%) | 74 (41.8%) |
Grade II | 474 (47.6%) | 388 (47.4%) | 86 (48.6%) |
Grade III | 222 (22.3%) | 205 (25.0%) | 17 (9.6%) |
T stage | |||
T1 | 187 (18.8%) | 125 (15.3%) | 62 (35.0%) |
T2 | 287 (28.8%) | 244 (29.8%) | 43 (24.3%) |
T3 | 522 (52.4%) | 450 (54.9%) | 72 (40.7%) |
Surgical approach | |||
Sweet | NA | 538 (65.7%) | NA |
Ivor-Lewis | NA | 23 (2.8%) | NA |
McKeown | NA | 129 (23.1%) | NA |
Other | NA | 69 (8.4%) | NA |
Age (year) | 59.3 ± 9.08 | 58.4 ± 9.24 | 63.5 ± 6.92 |
Hemoglobin (g/L) | 135.6 ± 14.59 | 136.6 ± 14.39 | 130.6 ± 14.54 |
Albumin (g/L) | 43.20 ± 3.89 | 43.16 ± 3.94 | 43.06 ± 3.69 |
Lymph nodes | 18.15 ± 12.50 | 18.3 ± 13.0 | 17.6 ± 9.2 |
Transthoracic laterality | |||
Left | 648 (65.1%) | 538 (65.7%) | 110 (62.1%) |
Right | 279 (28.0%) | 212 (25.9%) | 67 (37.9%) |
Other | 69 (6.9%) | 69 (8.4%) | 0 (0%) |