Fig. 2
From: Massive, life-threatening hemoptysis due to localized granulomatosis with polyangiitis
Histopathological findings, Haematoxylin and eosin stain. (A) Altered lung parenchima architecture, for the presence of extensive areas of chronic granulomatous, necrotizing (inset, asterisk) inflammation with numerous multinucleated histiocytic giant cells (arrows), in a palisading fashion. (B) Detail of necrotizing vasculitis affecting a medium-sized artery. (C) Particular of capillaritis, with septal capillaries filled with numerous neutrophils (arrow heads) and focal aspects of alveolar hemorrage (stars). Original magnification: A: 16X; A, inset: 100X; B and C: 200X