Table 3 Cox regression analyses for cancer-specific mortality of old patients
Univariable analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
Variables | HR | 95% CI | P-value | HR | 95% CI | P-value |
Sex | ||||||
Male | 1 | reference | 1 | reference | ||
Female | 0.754 | 0.558─1.077 | 0.121 | 0.880 | 0.603─1.285 | 0.508 |
Race | ||||||
White | 1 | reference | ||||
Other/ unknown | 1.448 | 0.912─2.298 | 0.117 | |||
Marital status | ||||||
Unmarried | 1 | reference | ||||
Married | 1.043 | 0.728─1.493 | 0.820 | |||
Unknown | 0.608 | 0.148─2.493 | 0.490 | |||
Location | ||||||
Upper | 1 | reference | 1 | reference | ||
Lower | 1.290 | 0.863─1.928 | 0.319 | 1.426 | 0.942─2.159 | 0.093 |
Other/ unknown | 1.994 | 1.082─3.677 | 0.027 | 1.511 | 0.779─2.931 | 0.222 |
Laterality | ||||||
Left | 1 | reference | ||||
Right | 0.956 | 0.670─1.364 | 0.805 | |||
T stage | ||||||
T1 | 1 | reference | 1 | reference | ||
T2 | 2.069 | 1.361─3.144 | 0.001 | 2.076 | 1.332─3.236 | 0.001 |
T3 | 2.082 | 1.097─3.953 | 0.025 | 1.778 | 0.904─3.498 | 0.096 |
T4 | 2.808 | 1.661─4.749 | < 0.001 | 2.009 | 1.096─3.681 | 0.024 |
N stage | ||||||
N0 | 1 | reference | 1 | reference | ||
N1 | 1.812 | 0.978─3.358 | 0.059 | 1.787 | 1.914─3.494 | 0.090 |
N2 | 2.883 | 1.955─4.251 | < 0.001 | 2.726 | 1.696─4.382 | < 0.001 |
Grade | ||||||
I─II | 1 | reference | ||||
III | 1.040 | 0.325─3.326 | 0.948 | |||
IV | 0.775 | 0.226─2.659 | 0.685 | |||
Unknown | 1.535 | 0.478─4.929 | 0.472 | |||
Surgery | ||||||
No | 1 | reference | 1 | reference | ||
Yes | 0.330 | 0.230─0.474 | < 0.001 | 0.278 | 0.169─0.457 | < 0.001 |
Radiotherapy | ||||||
No | 1 | reference | 1 | reference | ||
Yes | 1.405 | 0.970─2.035 | 0.072 | 0.623 | 0.377─1.027 | 0.064 |
Unknown | 1.482 | 0.466─4.709 | 0.505 | 1.182 | 0.352─3.975 | 0.787 |
Chemotherapy | ||||||
No | 1 | reference | 1 | reference | ||
Yes | 1.182 | 0.826─1.693 | 0.361 | 0.444 | 0.281─0.703 | 0.001 |