Fig. 5

Macroscopic and microscopic characteristics of the lesion. (A) The tumor occupies most of the length of the thoracic esophagus. (B) The entire wall of the esophagus is a tumor caused circumferential severe stricture and a minor normal part of the esophagus (green arrow). (C) The layers of the esophageal wall show strong fibrous proliferation with infiltration of many inflammatory cells. (D) The inflammatory cell component consists mainly of plasma cells (blue arrows) with lymphocytes with occasionally eosinophilic Russell bodies (yellow arrowheads). (H&E x 400)