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Table 2 Univariable and multivariable Cox proportional hazard regression analyses for mortality in trachea tumor patients

From: The impact of surgery and age on mortality with primary trachea malignant tumors: a retrospective study based on propensity-score matching analysis

 

Univariable analysis

Multivariable analysis

Variables

HR

P-Value

HR

95% CI

P-Value

Race/ ethnicity

     

 Caucasians

1

    

 Others

0.926

0.515

   

Sex

     

 Male

1

 

1

reference

 

 Female

0.813

0.036

0.885

0.721–1.086

0.242

Marital status

     

 Non-married

1

 

1

reference

 

 Married

0.707

0.001

0.742

0.603–0.913

0.005

 Unknown

0.923

0.684

0.847

0.568–1.264

0.417

Age (year)

     

 < 65

1

 

1

reference

 

 ≥ 65

2.103

< 0.001

1.905

1.548–2.344

< 0.001

Surgery

     

 No

1

 

1

reference

 

 Yes

0.276

< 0.001

0.371

0.265–0.520

< 0.001

 Other/ unknown

0.881

0.540

1.076

0.707–1.638

0.733

Chemotherapy

     

 No

1

 

1

reference

 

 Yes

1.392

0.001

0.845

0.683–1.045

0.120

Radiotherapy

     

 No

1

    

 Yes

0.943

0.576

   

 Unknown

0.831

0.590

   

Histological types

     

 SCC

1

 

1

reference

 

 SGC

0.260

< 0.001

0.396

0.286–0.550

< 0.001

 Other/unknown

0.644

< 0.001

0.783

0.616–0.997

0.047

Extension

     

 E1

1

    

 E2

1.145

0.457

0.769

0.528–1.120

0.171

 E3

1.504

0.004

1.213

0.881–1.671

0.237

 E4

2.565

0.002

1.403

0.718–2.740

0.322

 Ex

1.456

0.004

1.546

1.064–2.247

0.022

 N classification

     

 N0

1

 

1

reference

 

 N1

2.330

< 0.001

1.426

1.046–1.944

0.025

 Nx

1.376

0.004

2.185

1.364–3.502

0.001

M classification

     

 M0

1

 

1

reference

 

 M1

2.648

0.032

1.238

0.492–3.112

0.651

 M2

3.129

< 0.001

2.055

1.424–2.967

< 0.001

 Mx

1.087

0.430

0.342

0.205–0.568

< 0.001

Grade

     

 I-II

1

 

1

reference

 

 III-IV

1.526

0.001

1.337

1.029–1.737

0.030

 Unknown/other

1.005

0.966

1.068

0.837–1.363

0.596

Tumor size

     

 < 3.1 cm

1

 

1

reference

 

 3.1-5.0 cm

1.467

0.030

0.979

0.679–1.412

0.909

 > 5.0 cm

2.087

0.004

1.570

0.903–2.731

0.110

 Unknown

1.704

< 0.001

1.258

0.925–1.711

0.144

  1.  h: hazard ratio, CI: confidence interval, SCC: squamous cell carcinoma, SGC: salivary gland-type carcinoma
  2. Cox regression’s method was the Enter selection