Table 1 Study characteristics

Leshnower et al. [18]

2003

2017

Retrospective

ATAAD with MPS

ATAAD and MM

Central repair first in setting of MM

Carefully selected patients. CI to haemodynamic instability.

Haemodynamic instability /rupture

CT Cross sectional evidence of ischemia along with symptoms

Reported as individual patient data

13 TEVAR

3 ax-bifemoral bypass

10 hemiarch 2 root replacements

Yes

24 H after reperfusion

Yamashiro et al. [19]

2000

2014

Retrospective

ATAAD and visceral malperfusion

ATAAD and MM

Central repair first in setting of MM

Carefully selected patients. CI to haemodynamic instability,

Haemodynamic instability /rupture

CT Cross sectional evidence of ischemia along with symptoms

BE: −2.8 ± 1.2

Lactate 3.3 ± 1.2 a

Emergency Laparotomy/bypass before central repair

relook laparotomy post central repair

Not Specified

No

Not reported

Patel H et al. [20]

1997

2007

Retrospective

Patients with ATAAD malperfusion (all)

ATAAD and MM (subgroup)

No - Not specified for MM p

Carefully selected patients. CI to haemodynamic instability,

N/A

CT Cross sectional evidence of ischemia along with symptoms

Not reported

Angiography with percutaneous fenestration and aortic true lumen stenting with or without branch vessel stenting

N/A

No

median 4 days after reperfusion

Uchida et al. [21]

2006

2016

Retrospective

Patients with ATAAD and CT or clinical evidence of malperfusion (all types)

ATAAD and MM

Central repair first in setting of MM

Unclear – potentially change in protocol over later to contemporary time periods

Unclear – potentially change in protocol over later to contemporary time periods

CT Cross sectional evidence of ischemia along with symptoms

Not reported

Laparotomy and atom tube into SMA

Not Specified

No

Immediately after reperfusion

Deeb et al. [7]

1992

1996

Retrospective

Patients with ATAAD and CT or clinical evidence of malperfusion (all types)

ATAAD and MM

Central repair first in setting of MM

Unclear – potentially change in protocol over later to contemporary time periods

Unclear – potentially change in protocol over later to contemporary time periods

visceral: pain associated with physical findings compatible with an acute abdomen and associated abnormal laboratory findings.

Not reported

Fenestration of the aortic dissection flap accompanied by the stenting of compromised branch vessel

Root = 6, Hemiarch = 2, Ascending aorta = 1, total arch = 2

No

Median (days) 23 (IQR 2–57) after reperfusion

Yang et al. [22]

1996

2017

Retrospective

ATAAD with mesenteric malperfusion

ATAAD with MM

No (single arm study)

Carefully selected patients. CI to haemodynamic instability,

N/A

CT Cross sectional evidence of ischemia along with symptoms

7 ± 8.5 (max serum lactate mean)

IR, endovascular fenestration ± SMA stenting or suction thrombectomy if static obstruction

10 patients required further laparotomy and bowel resection.

Root replacement 14, Root repair 28, Arch 27, FET 2.

No

Median (days)

6 (IQR 2–19)

Tsagakis et al. [23]

2004

2011

Retrospective

ATAAD and malperfusion (All)

ATAAD with MPS

Yes – Central repair first in the setting of MM (subgroup)

Carefully selected patients. CI to haemodynamic instability,

Rupture/CPR and

other reasons:

Age less than 50 years (6/34), cardiogenic shock (17/34) Tamponade (5/34) previous coronary

angiograms (2/34) unavailability of the Hybrid OR (4/34)

CT Cross sectional evidence of ischemia along with symptoms

Not reported

All endovascular: four fenestrations, six splitting of the true limen,

Not Specified

Yes

Immediately after

Sugiyama et al. [24]

2017–2019

Retrospective

ATAAD with mesenteric malperfusion

ATAAD with MPS

Central repair first in setting of MM

Carefully selected patients. CI to haemodynamic instability,

Haemodynamic instability /rupture

CT Cross sectional evidence of ischemia along with symptoms

Not reported

Not reported

Hemiarch = 2, total arch = 2

Yes

Not reported