Fig. 2From: MicroRNA-185-5p targets tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta to regulate non-small cell lung cancer progressionmiR-185-5p overexpression inhibits cell proliferation, migration, invasion and promoted cell apoptosis of NSCLC cells. A miR-185-5p expression level in NCI-H1299 and PC9 after miR-185-5p mimic transfection was measured by qRT-PCR. B CCK-8 assay was used to assess the proliferation ability of NCI-H1299 and PC9 after miR-185-5p overexpression. C and D Transwell assay was used to assess the migration (C) and invasion (D) ability of NCI-H1299 and PC9 after miR-185-5p overexpression. E Cell apoptosis was measured by flow cytometry in NCI-H1299 and PC9 after miR-185-5p overexpression. F E-Cadherin, N-Cadherin and cleaved-caspase3 expression were measured by western blot in NCI-H1299 and PC9 after miR-185-5p overexpression. Each experiments included three biological replicates. The data was displayed as Mean ± SD. **p < 0.01, ***p < 0.001Back to article page