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Table 3 Univariate analysis of postoperative hemodynamic and laboratory variables

From: Risk factors associated with prolonged intensive care unit stay following surgery for total anomalous pulmonary venous connection: a retrospective study

Variable

Standard stay group (n = 62)

Prolonged stay group (n = 23)

P

pH on POD 1

7.360 ± 0.008

7.342 ± 0.015

0.255

PaO2on POD 1 (mmHg)

183.2 ± 10.55

237.07 ± 19.75

0.012

HB in POD 1 (g/L)

110.14 ± 2.28

106.83 ± 4.36

0.471

Lactate on POD 1 (mmol/L)

2.70 (1.88–4.43)

4.10 (3.20–5.10)

0.011

Blood calcium on POD 1 (mmol/L)

1.33 (1.23–1.44)

1.18 (1.12–1.35)

0.007

Volume of chest drainage over 24 h after surgery (ml/kg)

12.98 (8.31–18.76)

17.86 (11.70-26.79)

0.016

RBC infusion (u/kg)

0.46 (0.29–0.67)

1.33 (0.76–1.47)

< 0.001

FFP infusion (ml/kg)

69.09 ± 4.13

142.18 ± 13.83

< 0.001

IVS (mm)

   

POD 1

14.11 ± 1.26

22.21 ± 2.38

0.002

POD 2

10.35 ± 1.09

20.78 ± 2.66

0.001

POD 3

6.65 (0.58–11.75)

16.30 (12.40–24.70)

< 0.001

LVEF(%)

   

POD 1

67.15 ± 1.85

65.60 ± 3.36

0.663

POD 2

67.72 ± 1.42

66.50 ± 5.98

0.854

POD 3

66.70 ± 2.77

68.57 ± 0.97

0.537

CK-MB on POD 1 (U/L)

75.00 (60.50–93.50)

81.50 (58.50-114.75)

0.549

MAP(mmHg)

   

24 h after surgery

65.85 ± 1.08

63.70 ± 1.79

0.303

48 h after surgery

67.84 ± 0.85

62.13 ± 1.81

0.002

72 h after surgery

67.65 ± 0.90

65.17 ± 1.67

0.171

Arrhythmias (n/%)

46 (70.7%)

21 (91.3%)

0.047

Duration of mechanical ventilation (hours)

25 (22–47)

117(58–163)

< 0.001

Pneumonia (n/%)

52 (80.0%)

22 (95.6%)

0.283

Pneumonic consolidation (n/%)

6 (9.2%)

1 (4.3%)

0.726

Pneumothorax (n/%)

15 (23.1%)

7 (30.4%)

0.559

Renal function

   

Cystatin C (mg/L)

1.22 (0.97–1.48)

1.25 (1.05–1.35)

0.847

Peritoneal dialysis (n/%)

2 (3.1%)

1 (4.3%)

1.000

Liver function

   

ALT (U/L)

17.00 (12.75-23.00)

13.00 (8.00–19.00)

0.130

TBIL (mmol/L)

34.60 (18.93–91.20)

98.60 (35.00-129.10)

0.011

DBIL (mmol/L)

9.95 (5.95–12.40)

11.80 (9.50–16.10)

0.021

Coagulation function

   

PT (s)

13.80 (12.48–16.13)

14.30 (13.00-16.60)

0.392

APTT (s)

39.30 (32.45–43.38)

50.80 (37.50–59.10)

0.005

INR

1.19 (1.08–1.36)

1.19 (1.06–1.36)

0.74

  1. Abbreviations: pH, potential hydrogen; POD, postoperative day; PaO2, partial pressure of arterial oxygen; HB, hemoglobin; RBC, red blood cells; FFP, fresh-frozen plasma; IVS, interventricular septum; LVEF, left ventricular ejection fraction; CK-MB, creatine kinase MB isoenzyme; MAP, mean arterial pressure; ALT, alanine aminotransferase; TBIL, total bilirubin; DBIL, direct bilirubin; PT, prothrombin time; APTT, activated partial thromboplastin time; INR, international normalized ratio