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Fig. 3 | Journal of Cardiothoracic Surgery

Fig. 3

From: Stachydrine ameliorates hypoxia reoxygenation injury of cardiomyocyte via enhancing SIRT1-Nrf2 pathway

Fig. 3

STA enhances expressions of antioxidant-related proteins in cardiomyocytes with H/R. H9c2 cells were pretreated with 50 µM STA for 2 h and then subjected to H/R for 16 h. (a) Western blots were performed, and the representative protein bands are shown. The mean relative levels of SIRT1 (b), Nrf2 (c), and HO-1 (d) in H9c2 cardiomyocytes are shown. Values are expressed as Mean ± SD from at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 vs. control group; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. H/R group

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