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Table 5 Cox regression analysis for late all-cause mortality

From: N-terminal pro-B-type natriuretic peptide is associated with clinical outcomes after transcatheter aortic valve replacement

Variable

Univariate

Multivariate

HR (95%CI)

P value

HR (95%CI)

P value

NT-proBNP non-responders

2.434(1.226–4.830)

0.011

4.779(1.815–12.587)

0.002

Coronary artery disease

3.169(1.536–6.537)

0.002

2.974 (1.131–7.821)

0.027

Prior stroke

2.593(1.201–5.597)

0.015

——

——

Pure aortic insufficiency

2.506(1.034–6.072)

0.042

——

——

Length of hospitalization, increase by 1 day

1.039(1.022–1.057)

< 0.001

——

——

Intensive care unit, increase by 1 day

1.062(1.036–1.088)

< 0.001

1.051(1.018–1.084)

0.002

Mitral regurgitation ≥ moderate

2.449(1.062–5.647)

0.036

3.064(1.046–8.973)

0.041

Maximum velocity, increase by 1 m/s

0.726(0.554–0.951)

0.020

——

——

NT-proBNP ≥ 1350.5 pg/ml at discharge

4.864(2.260-10.468)

< 0.001

4.218(1.340-13.279)

0.014

  1. NT-proBNP, N-terminal pro–B-type natriuretic peptide; HR, hazard ratio; CI, confidence interval