Table 1 Summary of reported cases of alveolar adenoma from the literature
From: Enlarging pulmonary cyst: a rare form of alveolar adenoma
No. of cases | Age | Sex | Sx | Radiologic findings | Location | Max diameter (cm) | Work up | Treatment | Follow-up (mo) | Recurrence | Other malignancy |
|---|---|---|---|---|---|---|---|---|---|---|---|
6 [8] | 45 74 54 58 64 59 | F F F M M F | N Y N N N/A N | Solid nodule Solid nodule Solid nodule Solid nodule Solid nodule Solid nodule | LLL RML RUL LLL RUL RUL | 2.0 2.5 2.5 1.5 1.2 1.3 | CT, BRS (4) | Wedge Lobectomy Lobectomy Wedge Lobectomy Lobectomy | 13 120 12 56 13 | NED NED NED NED NED | Pituitary adenoma (1) |
1 [21] | 60 | F | Y | Solid nodule | LUL | 1.0 | CT | Wedge | None | ||
1 [32] | 67 | F | Y | Solid nodule | RML | 2.8 | CXR, unknown | Enucleation | 3 | NED | No comment |
1 [12] | 55 | F | Y | Solid mass | RLL | 4.0 | CT, BRS | Segmentectomy | 32 | NED | None |
1 [33] | 52 | F | N | Solid nodule | LLL | 2.0 | CT | Wedge | 12 | NED | No comment |
17 [10] | 45 58 50 39 41 52 41 54 64 58 45 68 46 NA 74 59 55 | M M M M F F F F M M F M F N/A F N/A F | N/A N N N N N N N N/A N N N/A N Y Y N Y | N/A Solid nodule Solid lesion Solid nodule Solid nodule Solid nodule Solid nodule Solid nodule Solid nodule Solid nodule Solid nodule Solid nodule Solid nodule Shadow Solid nodule Solid nodule Solid mass | LUL LLL LLL RLL LLL LLL LLL RUL RUL LLL LLL LLL N/A Right RML RUL RLL | 1.5 1.9 N/A 2.0 1.1 3.0 2.5 2.5 1.2 1.5 2.0 1.9 N/A 3.0 2.5 1.3 6.0 | CT, BRS (5) | Lobectomy (2) Wedge or other resection (8) Others: unknown but lung resection | FU in 5 pts (2, 2, 5, 8, 13 yrs) | NED | Melanoma Acromegaly Leiomyoma |
1 [16] | 47 | F | Y | Solid nodules Solid nodules Solid nodules | LLL RUL LLL | 2.0 1.0 1.0 | CT, MRI, BRS | Wedge (LLL) | 15 | NED | None |
1 [13] | 34 | F | Y | Solid nodule | LUL | 1.6 | CT, BRS | Wedge | 12 | NED | No comment |
1 [28] | 51 | F | Y | Solid mass with cystic lesion | RUL | 3.4 | CT, BRS | Sublobar resection | 18 | No comment | |
1 [24] | 69 | M | N | Solid and cystic lesion | RUL | 3.5 | CT, BRS | Wedge | 13 | NED | None |
1 [34] | 43 | M | Y | Solid and cystic component | LLL | 1.1 | XR, CT, PET | Wedge, LNS | 18 | NED | None |
2 [11] | 62 54 | M M | Y N | Solid nodule Solid nodule | LLL LLL | 1.5 4.0 | CXR, MRI CXR, No comment | Segmentectomy Wedge | 22 32 | NED NED | No comment |
1 [31] | 71 | M | N | Solid nodule | RLL | 1.7 | CT | Segmentectomy | Prostate cancer | ||
1 [30] | 58 | F | Y | Solid nodule | LUL | 0.8 | CT | Partial lung resection | 3 | NED | None |
1 [18] | 38 | F | Y | Cystic mass | LUL | 9.1 | CT | Partial lung resection | No comment | ||
1 [35] | 61 | F | N | Solid nodule | LUL | 2.4 | CT, PET | Segmentectomy | 12 | NED | None |
1 [36]** | 59 | M | N | Incidental on pathology specimen | RUL | 0.2 | CT | Lobectomy | Lung cancer (SqCC) | ||
1 [37] | 42 | F | N | Solid nodule | RLL | 1.2 | CT | Wedge | 12 | NED | No comment |
1 [14] | 54 | F | Y | Solid nodule | LLL | 1.8 | CT, PET, Brain CT, Abdomen CT, BRS | Lobectomy | 12 | NED | Gastric cancer |
2 [17] | 24 35 | M F | N Y | Solid nodule Solid mass | LLL RUL | 1.8 5.0 | CT, PET CT | Wedge Wedge | 7 132 | NED NED | No comment No comment |
1 [9] | 60 | F | N | Solid nodule | RLL | 7.0 | CT, MRI | Wedge | 6 | NED | Cysts in breast, liver, kidney |
1 [29] | 48 | F | N | Solid mass | RLL | 4.0 | CT, MRI, bronchoscopy | Lobectomy | 48 | NED | No comment |
1 [27] | 67 | M | Y | Solid and cystic lesion | RLL | 3.9 | CT | Wedge | No comment | ||
1 [38] | 47 | F | N | Round mass with air inclusions (“abscess”) | RLL | 4.0 | CT | Segmentectomy | 52 | NED | Cerebral AVM |
1 [23] | 83 | M | N | Solid nodule | LUL | 1.8 | CT, PET, BRS | Segmentectomy | 48 | NED | No comment |
1 [15] | 40 | M | Y | Solid mass | LLL | 5.1 | CT | Lobectomy | 26 | NED | No comment |
1 [39] | 48 | F | N | Solid mass | LLL | 3.5 | CT | Lobectomy | 60 | NED | Bronchogenic cyst |
4 [20] | 36 51 38 59 | M F F F | Y Y Y Y | Solid nodule Solid nodule Solid nodule Solid nodule | LLL RUL RUL LLL | 2.6 1.8 1.3 2.0 | CT, PET, BRS CT, BRS CT, RS CT, BRS | Resection Wedge Wedge Wedge | 34 180 120 96 | NED NED NED NED | No comment |
1 [40] | 59 | F | Y | Ground glass nodule | RUL | 2.4*(7.4) | CT, Bone scan, Brain CT | Lobectomy | 36 | NED | No comment |
1 [22] | 48 | F | Y | Solid nodule | LUL | 1.2 | CT, PET | Wedge | Colon tubulovillous adenoma, Pituitary adenoma | ||
1 [19] | 26 | F | Y | Multicystic bullae | LUL | 3.2 | CT | Lobectomy | No comment | ||
1 [6] | 63 | M | N | Solid nodule | LLL | 4.0 | CT, BRS | Lobectomy | 12 | NED | No comment |
1 [7] | 52 | F | N | Solid nodule | RUL | 1.2 | CT, PET | Wedge | 36 | NED | Incidental AAH |