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Table 4 Baseline characteristics of patients with no frailty compared with patients with frailty

From: Pre-treatment optimisation with pulmonary rehabilitation of elderly lung cancer patients with frailty for surgery

Parameter

FI ≤ 3 vs. FI > 3

< 70,FI ≤ 3 vs. ≥70,FI > 3

  

FI ≤ 3

(n = 141)

FI > 3

(n = 80)

P

< 70,FI ≤ 3 (n = 57)

≥ 70,FI > 3 (n = 57)

p

Gender

M:F

69:72

36:44

ns

27:30

28:29

ns

Age (years)

Mean (± 95%CI)

72.9 ± 1.6

70.9 ± 1.3

0.034

63. 9 ± 1.2

76.7 ± 1.1

< 0.00001

Stage of lung cancer

I

II

III

IV

93 (66)

22 (15.6)

25 (17.7)

1 (0.7)

56 (70)

12 (15)

12 (15)

-

ns

19 (33.3)

28 (49.1)

10 (17.5)

-

44 (77.2)

8 (14.1)

5 (8.8)

ns

Performance status

0–1

2–4

114 (82)

25 (18)

16 (41.2)

64 (58.8)

0.00001

43 (78.2)

12 (21.8)

13 (22.8)

44 (77.2)

< 0.00001

Dyspnoea score

0–2

3–4

101 (72.7)

38 (27.3)

19 (23.7)

61 (76.3)

0.00001

36 (65.5)

19 (34.5)

11 (19.3)

46 (80.7)

< 0.00001

Level of activity

Sedentary

Active

57 (40.7)

83 (59.2)

77 (96.3)

3 (3.7)

0.00001

25 (44.6)

31 (55.4)

55 (96.5)

2 (3.5)

< 0.00001

Smoking habit

Current smoker

Previous smokers

20 (14.2)

102 (72.3)

19 (13.5)

21(26.3)

51 (63.75)

8 (10)

0.07

14 (24.6)

36 (63.1)

7 (12.3)

8 (14.0)

42 (73.7)

7 (12.3)

ns

Smoking cessation advice

Yes

Declined

No

14 (66.7)

5 (23.8)

2 (9.5)

16 (84.2)

2 (10.5)

1 (5.3)

ns

11 (78.6)

2 (14.3)

1 (7.1)

4 (50)

2 (25)

2 (25)

ns

FEV1 (litres)

Mean (± 95%CI)

1.84 ± 0.11

1.81 ± 0.37

ns

1.86 ± 0.2

1.79 ± 0.2

ns

FEV1 (% predicted)

Mean (± 95%CI)

79.85 ± 4.2

82.81 ± 4.8

ns

72.4 ± 6.6

83.8 ± 6.1

0.007

DLCO (% predicted)

Mean (± 95%CI)

71.9 ± 3.1

63.46 ± 3.7

0.0005

68.94 ± 4.6

63.42 ± 4.7

0.05

Thoracoscore (%)

Mean (± 95%CI)

2.1 ± 0.3

3.33 ± 0.5

0.00002

1.78 ± 0.3

3.49 ± 0.7

< 0.00001

6MWT (mts)

Mean (± 95%CI)

378.11 ± 17.7

218.68 ± 24.1

0.00001

399.69 ± 29.6

211.82 ± 26.3

< 0.00001

Sessions of Prehab

Mean (± 95%CI)

3.7 ± 0.7

3.6 ± 1.1

ns

3.31 ± 0.9

3.24 ± 1.4

ns

Assessment to surgery days

Mean (± 95%CI)

44.06 ± 8.5

62.44 ± 18.7

0.02

37.42 ± 12.5

56.6 ± 16.0

0.04

Considered not fit for

Surgery

Radical treatment

47 (33.3)

45 (31.9)

66 (82.5)

27 (36.9)

0.00001

ns

20 (35.1)

18 (31.6)

50 (87.7)

11 (26.2)

< 0.00001

0.0066

  1. Values are numbers (percentage) unless otherwise stated. CI = confidence interval.
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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