Table 6 Outcomes following Prehab and surgery in low risk patients with no Frailty compared with the high risk patients with Frailty
Parameter | FI ≤ 3 vs. FI > 3 | < 70,FI ≤ 3 vs. ≥70,FI > 3 | |||||
|---|---|---|---|---|---|---|---|
FI ≤ 3 (n = 141) | FI > 3 (n = 80) | P | < 70,FI ≤ 3 (n = 57) | ≥ 70,FI > 3 (n = 57) | p | ||
Type of surgery | Lobectomy Segmentectomy Pneumonectomy Wedge resection Endobronchial excision Thoracotomy Failed OLV trial | 98 (69.5) 15 (10.6) 3 (2.1) 24 (17.0) 1 (0.7) | 42 (52.5) 11 (13.8) - 21 (26.3) 2 (2.5) 3 (3.7) 1 (1.2) | 0.078 | 39 (68.4) 5 (8.8) 1 (1.8) 11 (19.3) 1 (1.8) | 31 (55.4) 7 (12.5) - 14 (25) 2 (3.6) 1 (1.8) 1 (1.8) | ns |
Surgical approach | Minimally invasive Thoracotomy Failed OLV trial | 88 (62.4) 53 (37.6) | 47 (58.8) 32 (40) 1 (1.2) | ns | 35 (61.4) 22 (38.6) | 35 (45.6) 21 (36.8) 1 (1.8) | ns |
HDU | Median (IQR) | 4 (2) | 3 (3) | ns | 3 (3) | 3 (3) | ns |
Ward | Median (IQR) | 3 (3.7) | 3 (3) | ns | 3 (4) | 3 (3) | ns |
LOHS | Median (IQR) | 8 (5.5) | 7 (6.8) | ns | 8 (7) | 7 (6.5) | ns |
Complications | Major | 13 (9.2) | 7 (8.8) | ns | 8 (14.0) | 6 (10.5) | ns |
Cardio-respiratory events | Cardiac: Atrial fibrillation Major cardiac events Hypotension/hypertension Respiratory: Air leak Lobar collapse/consolidation Respiratory infection/retained secretions Pleural effusion/excessive drainage Pneumothorax/Surgical emphysema (mild) | 13 (19) 1 (1.4) 1 (1.4) 5 (7.1) 3 (4.3) 17 (24.3) 4 (5.7) 6 (8.6) | 5 (12.2) 2 (4.8) 1 (2.4) 1 (2.4) 5 (12.2) 12 (29.3) - 4 (9.7) | ns ns | 4 (7.0) 0 1 (1.8) 2 (3.5) 2 (3.5) 11 (19.3) 1 (1.7) 3 (5.3) | 5 (8.8) 1 (1.8) 2 (3.5) 0 2 (3.5) 11 (19.3) 0 2 (3.5) | ns ns |
Recidivism | 8 (5.7) | 2 (2.5) | ns | 4 (7.0) | 2 (3.5) | ns | |
Post-operative Mortality | In-hospital | 1 (0.7) | 1 (1.2) | ns | 1 (1.8) | (1 (1.8) | |
30 days | 1 (0.7) | 3 (3.7) | ns | 1 (1.8) | 2 (3.5) | ns | |
90 days | 4 (2.8) | 5 (6.3) | ns | 3 (5.3) | 3 (5.3) | ns | |
1 year | 21 (14.9) | 16 (20) | ns | 8 (14.0) | 12 (21) | ns | |
% Survival (range) | 365 days (CI) 1100 days (CI) | 85.0 (75.1–1.2) 71.1 (58.2–80.7) | 80.0 (72.4–85.7) 63.2 (53.6–71.4) | ns ns | 85.96 (73.9–92.7) 79.96 (66.9–88.4) | 76.8 (63.7–85.9) 55.2 (39.9–68.1) | ns 0.01 |