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Table 1 Baseline characteristics of participants

From: An individualized nomogram for predicting and validating spread through air space (STAS) in surgically resected lung adenocarcinoma: a single center retrospective analysis

Characteristics

Training group

Validation group

P Value

No. of cases

188

53

Period of diagnosis

2019.1 ~ 2019.12

2022.1 ~ 2022.6

Age

≤ 65 y

109 (58)

28 (52.8)

0.504

>65y

79 (42)

25 (47.2)

Sex

Male

91 (48.4)

26 (49.1)

0.933

Female

97 (51.6)

27 (50.9)

Tumor site

Inferior left

32(17)

8(15.1)

0.722

Superior left

47(25)

10(18.9)

Inferior right

36(19.1)

14(26.4)

Middle right

11(5.9)

4(7.5)

Superior right

62(33)

17(32.1)

Surgical approach

Lobectomy

106(56.4)

25(47.2)

0.234

Sublobar resection

82(43.6)

28(52.8)

CEA

>5

39(20.7)

8(15.1)

0.359

≤ 5

149(79.3)

45(84.9)

NSE

>17

8(4.3)

9(17)

0.004

≤ 17

180(95.7)

44(83)

Cyfra21-1

>3.3

58(30.9)

11(20.8)

0.151

≤ 3.3

130(69.1)

42(79.2)

CA199

>34

7(3.7)

1(1.9)

0.822

≤ 34

181(96.3)

52(98.1)

CA724

>8.2

13(6.9)

10(18.9)

0.009

≤ 8.2

175(93.1)

42(81.1)

CA125

>35

8(4.3)

2(3.8)

1.000

≤ 35

180(95.7)

51(96.2)

NLR

 

2.22(1.68,2.92)

2.36 (1.81,3.42)

0.102

PLR

 

131.64 (105.30,164.36)

139.61 (111.65,169.08)

0.229

CT size

 

16 (12,25)

16 (12,23.5)

0.579

CTR

>75%

90(47.9)

14(26.4)

0.013

50%~75%

22(11.7)

14(26.4)

25%~50%

34(18.1)

11(20.8)

≤ 25%

42(22.3)

14(26.4)

TNM stage

I + II

168(79.4)

50(94.3)

0.276

III + IV

20(20.6)

3(5.7)

STAS

+

41(21.8)

11(20.8)

0.869

-

147(20.8)

42(79.2)