Table 1 Population characteristics
Overall (n = 80) | SAVR (n = 40) | TAVR (n = 40) | p | |
|---|---|---|---|---|
Clinical characteristics | ||||
Age [year (median IQR)] | 76.5 [70,83] | 72 [63,75] | 81 [74,88] | < 0.001 |
Blood pressure (mm Hg) | ||||
Male gender | 52 (65) | 28 (70) | 24 (60) | 0.48 |
Bicuspid aortic valve | 16 (20) | 13 (32.5) | 3 (7.5) | 0.012 |
Pre-AVR AS severity | 1 | |||
Moderate | 1 (1.2) | 1 (2.5) | 0 | |
Severe | 79 (98.8) | 39 (97.5) | 40 (100) | |
Clinical risk factors | ||||
Coronary artery disease | 32 (40) | 12 (30) | 20 (50) | 0.11 |
Hypertension | 57 (71.2) | 26 (65) | 31 (77.5) | 0.32 |
Hyperlipidemia | 51 (63.7) | 24 (60) | 27 (67.5) | 0.64 |
Diabetes mellitus | 18 (22.5) | 8 (20) | 10 (25) | 0.77 |
NYHA ≥ 2 | 68 (85) | 29 (72.5) | 39 (97.5) | 0.005 |
Intraoperative data | ||||
Valve size (mm, median [IQR]) | 25 [23,26] | 23 [23,25] | 26 [23,29] | < 0.001 |
Edwards (Magna/Inspiris resilia; Sapien 3) | 33 (82.5) | 35 (87.5) | ||
Medtronic (Mosaic Valve/Avalus; Core valve) | 7 (17.5) | 5 (12.5) | ||
Mean gradient | ||||
Pre-AVR | 40.5 [30.2,47] | 38.8 [29.8,45.5] | 41 [33.6,47.7] | 0.33 |
post-AVR | 6 [4, 9] | 8 [5.5,11] | 4 [3, 6] | < 0.001 |
Pulse pressure | ||||
Use of inotropes* | 29 (36.2) | 27 (67.5) | 2 (5) | < 0.001 |
Use of vasopressors** | 23 (29.1) | 9 (23.1) | 14 (35) | 0.36 |