Distal aortic biomechanics after transcatheter versus surgical aortic valve replacement: a hypothesis generating study

Table 2 Descending Aortic Biomechanics Before and After Interventions

	SAVR (n = 40)			TAVR (n = 40)
	Pre	Post	p	Pre	Post	p
Global circumferential strain, GCS [%]	4.4 [3.3,5.3]	4.7 [3.9,5.6]	0.32	10.7 [4.5,14.6]	17.0 [6.1,20.9]	0.009
Pulse pressure corrected strain [%/mm Hg] (GCS/PP)	6.8 [5.5,9.2]	7.6 [6.1,10.8]	0.20	13.6 [8.6,23.5]	26.8 [10.6,32.0]	0.012
Time to peak strain, TTP [ms]	300 [270,334]	195 [167,250]	< 0.001	315 [285,400]	300 [280,385]	0.33
Δ Αrea/TTP [cm²/s]	1.3 [0.9,1.9]	2.5 [1.8,3.1]	< 0.001	2.2 [1.5,3.7]	2.6 [1.8,4.2]	0.22
Distensibility [10^–3 mmHg⁻¹]	1.5 [1.1,2.0]	1.4 [1.1,1.7]	0.52	3.6 [1.9,6.7]	4.9 [1.4,7.6]	0.76
Δ Αrea [cm²]	0.4 [0.3,0.6]	0.5 [0.4,0.6]	0.11	0.9 [0.4,1.2]	0.7 [0.6,1.4]	0.53
Fractional area change [%]	9.4 [6.8,11.9]	10.5 [9.3,13.5]	0.09	30.0 [9.1,40.8]	32.9 [103,57.1]	0.22
End systolic area [cm²]	5.3 [4.1,5.9]	4.8 [4.1,6.0]	0.81	4.6 [3.7,5.6]	4.4 [3.3,5.7]	0.90
End diastolic area [cm²]	4.8 [3.7,5.7]	4.3 [3.6,5.4]	0.65	3.3 [2.6,4.9]	3.3 [2.5,4.7]	0.76

cm centimeters, GCS Global circumferential strain [%], ms milliseconds, PP pulse pressure, SAVR surgical aortic valve replacement, TAVR transcatheter aortic valve replacement, TTP, time to peak

ISSN: 1749-8090