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Table 4 Biomechanical variables before and after interventions

From: Distal aortic biomechanics after transcatheter versus surgical aortic valve replacement: a hypothesis generating study

 

Overall

(n = 80)

SAVR

(n = 40)

TAVR

(n = 40)

P

Pre-procedure strain variables

    

 GCS (%)

5.2 [3.4,10.7]

4.4 [3.3,5.3]

10.7 [4.5,14.6]

 < 0.001

 Pulse pressure-corrected strain (GCS/PP)

9.1 [6.3,14.6]

6.8 [5.5,9.2]

13.6 [8.6,23.5]

 < 0.001

 TTP (ms)

300 [270,370.3]

300 [270,334]

315 [285,400]

0.14

 ΔΑrea/TTP [cm2/s]

1.7 [1.04,2.5]

1.3 [0.9,1.9]

2.2 [1.5,3.7]

0.001

Distensibility (10−3 mmHg)

2 [1.3,4.2]

1.5 [1.1,2.04]

3.6 [1.9,6.7]

 < 0.001

 FAC (%)

10.7 [7.4,29.8]

9.35 [6.8,11.9]

30 [9.4,40.8]

 < 0.001

 ESA (cm2)

4.8 [3.8,5.7]

5.3 [4.07,5.9]

4.6 [3.7,5.6]

0.12

 EDA (cm2)

4.1 [3.1,5.3]

4.8 [3.7,5.6]

3.3 [2.6,4.9]

0.002

Post-procedure strain variables

    

 GCS (%)

5.6 [4.1,16.23]

4.65 [3.9,5.6]

17 [6.1,20.9]

 < 0.001

 Pulse pressure-corrected strain (GCS/PP %)

10.8 [6.3,26.5]

7.6 [6.1,10.8]

26.8 [10.6,32]

 < 0.001

 TTP (ms)

263.5 [187.5,305]

195 [166.8,250]

300 [280,385]

 < 0.001

 Δ Αrea/TTP [cm2/s]

2.6 [1.8,3.6]

2.5 [1.8,3.1]

2.6 [1.8,4.2]

0.26

 PP (mmHg)

61 [47.8,72.3]

60 [46.8,67.5]

63 [50.8,77]

0.08

Distensibility (10−3 mmHg)

1.6 [1.2,4.95]

1.4 [1.1,1.7]

4.9 [1.4,7.6]

 < 0.001

 FAC (%)

12.3 [9.5,35.2]

10.5 [9.3,13.5]

32.9 [10.3,57.1]

 < 0.001

 ESA (cm2)

4.6 [3.7,5.9]

4.8 [4.1,6.0]

4.3 [3.3,5.7]

0.14

 EDA (cm2)

3.9 [2.9,5]

4.3 [3.6,5.4]

3.3 [2.5,4.7]

0.002

  1. All values were (median [interquartile range])
  2. cm Centimeters, EDA End diastolic area, ESA End systolic area, FAC Fractional area change, GCS Global circumferential strain [%], ms Milliseconds, PP Pulse pressure, SAVR Surgical aortic valve replacement, TAVR Transcatheter aortic valve replacement, TTP Time to peak