Table 1 The clinical characteristics of 574 GGNs.
Benign (n = 93) | Malignant (n = 481) | p-value | |
|---|---|---|---|
Age(years) | 52.76 ± 9.754 | 52.59 ± 11.302 | 0.735 |
Gender | 0.009 | ||
Male | 40 | 141 | |
Female | 53 | 340 | |
Follow-up time | 0.098 | ||
Less than one month | 27 | 102 | |
More than one month | 66 | 379 | |
Histories of malignant tumors | 6 (6.5%) | 20 (4.2%) | 0.330 |
Smoking history | 20 (21.5%) | 67 (13.9%) | 0.062 |
Maximum diameter of GGNs (mm) | 0.865 ± 0.350 | 1.045 ± 0.360 | < 0.001 |
Location | 0.024 | ||
RUL | 28 | 176 | |
RML | 9 | 33 | |
RLL | 19 | 84 | |
LUL | 17 | 134 | |
LLL | 20 | 54 | |
Shape | 0.370 | ||
Round/oval | 61 | 338 | |
Irregular | 32 | 143 | |
Lobulation | 9 (9.7%) | 62 (12.9%) | 0.389 |
Spinous process | 0 | 1 (0.2) | 0.660 |
Vacuole sign | 12 (12.9%) | 325 (67.6%) | < 0.001 |
Air bronchogram | 1 (1.1%) | 104 (21.6%) | < 0.001 |
Intra-nodular vessel sign | 11 (11.8%) | 378 (78.6%) | < 0.001 |
Calcification and fat | 0 | 0 | / |
Necrosis | 0 | 0 | / |
Pleural indentation | 6 (6.5%) | 17 (3.5%) | 0.189 |
Pleural effusion | 0 | 0 | / |
Emphysema | 2 (2.2%) | 6 (1.2%) | 0.496 |
Pulmonary fibrosis | 0 | 0 | / |
Other nodules | 28 (30.1%) | 176 (36.6%) | 0.232 |