Surgical outcomes and perioperative risk factors of patients with interstitial lung disease after pulmonary resection

Table 3 Clinical characteristics and outcome of patients with postoperative AE-ILD

Gender /Age	Smoking index^a/Quitting time	Comorbidity	PFT FEV₁/MVV/DLCO (% pred)	Type and history of ILD	Image feature and range of ILD	Pathology and TNM stage	Surgery	Operation time (min)	Intraoperative blood loss (ml)	Onset of AE-ILD	Treatment	Outcome
M/74	30/180mo	None	80/84/53	IPF/3mo	UIP/whole lung field	SCLC/III-a	L + SLND/VATS	105	350	POD 2	Glucocorticoid /IMV	Died, POD 15
M/73	50/36mo	COPD, CHD	63.6/48.4/57.4	IPF/36mo	UIP/whole lung field	SCC/Ia2	W + SLND/VATS	75	30	POD 52	NIV	Improve
M/76	75/0.5mo	COPD, CHD, AF, renal carcinoma	92.8/93.4/64.9	IPF/36mo	UIP/bilateral subpleural area	SCLC/Ia1	W + SLND /VATS	60	20	POD 5	Glucocorticoid	Improve
M/60	150/1mo	CHD, DM	69/86/67	IPF/240mo	UIP/bilateral subpleural area	SCLC/IIb	L + SLND /VATS	160	200	POD 3	Glucocorticoid /NIV	Improve
M/74	50/1mo	HTN, SS, glomerular nephritis	88/134/66	CTD-ILD/48mo	Non-UIP/bilateral subpleural area	SCLC/IIIa	L + SLND /VATS	230	600	POD 3	Glucocorticoid /IMV	Died, POD 38
F/73	non-smoker	HTN, SS	60/92/64	CTD-ILD/48mo	Non-UIP/bilateral subpleural area	IP	L/VATS	160	600	POD 3	Glucocorticoid /NIV	Died, POD 13
M/70	non-smoker	CHD, DM	107.4/89/61.6	IPF/unknown	UIP/bilateral subpleural area	IP	S + W/VATS	100	50	POD 30	Glucocorticoid /NIV	Died, POD 60

Note: a: package-years
Abbreviation: AE-ILD: acute exacerbation of interstitial lung disease; AF: atrial fibrillation; CHD: coronary heart disease; COPD: chronic obstructive pulmonary disease; CTD-ILD: Connective tissue diseases related interstitial lung disease; DLCO: diffusing capacity of carbon monoxide; DM, diabetes mellitus; F: female; FEV1: forced expiratory volume in 1 s; HTN, hypertension; ILD: interstitial lung disease; IMV: invasive mechanical ventilation; IP: Inflammatory pseudotumor; IPF: idiopathic pulmonary fibrosis; L: lobectomy; M: male; min: minute; ml: milliliter; mo: month; MVV: maximal voluntary ventilation; NIV: Non-invasive ventilation; PFT: pulmonary function test; POD: postoperative day; S: segmentectomy; SCC: Squamous cell carcinoma; SCLC: Small cell carcinoma; SLND: systematic lymph node dissection; SS: Sjogren Syndrome; UIP: usual interstitial pneumonitis; VATS: video-assisted thoracoscopic surgery; W: wedge resection;

ISSN: 1749-8090