Table 4 Univariate logistic regression analysis of risk factors for postoperative 90-day complications

Age (> 65)

45 (57.7)

2.8

0.899–8.717

0.076

Gender (male)

64 (84.2)

1.326

0.330–5.335

0.691

Smoking history

 Non-smoker

34 (43.6)

1.000

-

 Ex-smoker

20 (25.6)

1.538

0.405–5.842

0.527

 Current smoker

24 (30.8)

3.333

0.824–13.482

0.091

Smoking index (package-years)

1.006

0.992–1.020

0.406

Comorbidity

58 (74.4)

9.256

1.151–74.412

0.036

Age-adjusted Charlson Comorbidity Index

 Score ≤ 3

44 (56.4)

1.000

-

0.002

 Score > 4

34 (43.6)

6.158

1.948–19.470

PFT

 FEV₁ (% pred) < 70%

34 (43.6)

0.821

0.292–2.306

0.708

 FVC (% pred) < 70%

24 (30.8)

0.684

0.216–2.163

0.518

 FEV₁/FVC (% pred) < 70%

21 (26.9)

0.875

0.273–2.804

0.822

 MVV (% pred) < 70%

36 (46.2)

0.714

0.254–2.005

0.523

 DLCO (% pred) < 60%

31 (39.7)

1.339

0.479–3.744

0.578

Preoperative prophylaxis for ILD

17 (21.8)

1.278

0.387–4.221

1.278

History of AE-ILD

14 (17.9)

1.815

0.527–6.251

0.345

Surgical approach

 VATS

68 (87.2)

1.000

-

 Thoracotomy

10 (12.8)

1.286

0.299–5.534

0.736

Extent of resection

 Sublobectomy

49 (62.8)

1.000

-

-

 Lobectomy or more

29 (37.2)

3.618

1.256–10.424

0.017

Systematic lymph node dissection

50 (64.1)

4.293

1.132–16.278

0.032

Operation time (min)

1.010

1.002–1.018

0.011

Intraoperative blood loss (ml)

1.005

1.001–1.008

0.008

Intraoperative accident or blood transfusion

12 (15.4)

0.412

0.114–1.487

0.176

Pathology of pulmonary lesion

 Benign

28 (35.9)

1.000

-

 Malignant

50 (64.1)

4.293

1.132–16.278

0.032