Table 1 Heart failure group characteristics
From: Determinants of survival following heart transplantation in adults with congenital heart disease
Ischemic cardiomyopathy (n = 14,236) | Nonischemic cardiomyopathy (n = 20,676) | Congenital cardiomyopathy (n = 1040) | P value | |
|---|---|---|---|---|
Recipient preoperative features | ||||
Demographics: age | 58.37 ± 8.02 | 50.11 ± 13.08 | 35.49 ± 12.99 | < 0.001 |
Male | 12,408 (87.2%) | 14,009 (67.8%) | 633 (60.9%) | < 0.001 |
Weight (kg) | 83.89 ± 15.94 | 81.58 ± 18.61 | 71.20 ± 18.43 | < 0.001 |
Height (cm) | 174.74 ± 8.81 | 173.46 ± 10.36 | 169.33 ± 10.92 | < 0.001 |
BMI | 27.40 ± 4.44 | 26.97 ± 5.06 | 24.67 ± 5.27 | < 0.001 |
Donor/recipient BMI ratio | 1.01 ± 0.23 | 1.02 ± 0.25 | 1.06 ± 0.26 | < 0.001 |
BSA | 2.01 ± 0.22 | 1.97 ± 0.26 | 1.82 ± 0.27 | < 0.001 |
Donor/recipient BSA ratio | 0.99 ± 0.12 | 1.01 ± 0.13 | 1.04 ± 0.14 | < 0.001 |
Comorbidities: creatinine (mg/dL) | 1.39 ± 0.83 | 1.33 ± 0.95 | 1.21 ± 0.81 | < 0.001 |
Bilirubin (mg/dL) | 1.06 ± 1.97 | 1.14 ± 2.00 | 1.21 ± 1.74 | < 0.001 |
Diabetes | 3888 (27.3%) | 3527 (17.1%) | 53 (5.1%) | < 0.001 |
Dialysis | 609 (4.3%) | 815 (3.9%) | 44 (4.2%) | 0.288 |
Cerebrovascular disease | 764 (5.4%) | 988 (4.8%) | 53 (5.1%) | 0.047 |
Malignancy history | 813 (5.7%) | 1,671 (8.1%) | 25 (2.4%) | < 0.001 |
Presentation acuity: days in status 1A | 22.87 ± 46.52 | 28.09 ± 55.72 | 28.70 ± 73.33 | < 0.001 |
Days in status 1B | 82.93 ± 168.54 | 87.84 ± 176.33 | 85.95 ± 176.58 | 0.034 |
Days in status 2 | 96.35 ± 259.41 | 67.51 ± 209.16 | 148.75 ± 292.49 | < 0.001 |
Mechanical support: left ventricular assist device | 4,146 (29.1%) | 6,371 (30.8%) | 62 (6.0%) | < 0.001 |
Right ventricular assist device | 23 (0.2%) | 33 (0.2%) | 7 (0.7%) | 0.001 |
Biventricular support or TAH | 328 (2.3%) | 759 (3.7%) | 17 (1.6%) | < 0.001 |
Extracorporeal membrane oxygenation | 53 (0.4%) | 111 (0.5%) | 16 (1.5%) | < 0.001 |
Intra-aortic balloon pump | 943 (6.6%) | 1,157 (5.6%) | 26 (2.5%) | < 0.001 |
Hemodynamics: cardiac output (L/min) | 4.68 ± 1.35 | 4.45 ± 1.47 | 4.42 ± 1.30 | < 0.001 |
Systolic pulmonary artery pressure (mmHg) | 41.67 ± 14.09 | 40.87 ± 13.24 | 37.31 ± 15.00 | < 0.001 |
Diastolic pulmonary artery pressure (mmHg) | 19.19 ± 7.99 | 20.07 ± 8.44 | 18.21 ± 7.60 | < 0.001 |
Mean pulmonary artery pressure (mmHg) | 27.67 ± 9.62 | 27.99 ± 9.60 | 25.10 ± 9.74 | < 0.001 |
Pulmonary capillary wedge pressure (mmHg) | 18.10 ± 8.22 | 18.58 ± 8.43 | 16.91 ± 6.78 | < 0.001 |
Donor: age | 32.30 ± 12.00 | 31.61 ± 11.66 | 28.13 ± 11.23 | < 0.001 |
Male | 10,606 (74.5%) | 14,251 (68.9%) | 667 (64.1%) | < 0.001 |
Weight (kg) | 82.92 ± 17.87 | 81.65 ± 19.12 | 74.99 ± 18.17 | < 0.001 |
Height (cm) | 175.10 ± 9.21 | 173.84 ± 9.78 | 171.47 ± 10.56 | < 0.001 |
BMI | 27.05 ± 5.52 | 26.99 ± 5.83 | 25.43 ± 5.41 | < 0.001 |
BSA | 2.00 ± 0.24 | 1.97 ± 0.25 | 1.88 ± 0.26 | < 0.001 |
Left ventricular ejection fraction (%) | 61.58 ± 7.28 | 61.63 ± 7.08 | 62.18 ± 7.55 | 0.034 |
Heart ischemic time (h) | 3.20 ± 1.06 | 3.12 ± 1.02 | 3.50 ± 1.15 | < 0.001 |
Coronary artery disease | 3,576 (25.1%) | 5,213 (25.2%) | 193 (18.6%) | < 0.001 |
Hypertension | 1,985 (13.9%) | 2,902 (14.0%) | 120 (11.5%) | 0.076 |
Diabetes | 430 (3.0%) | 617 (3.0%) | 23 (2.2%) | 0.332 |
Cocaine history | 2,242 (15.7%) | 3,461 (16.7%) | 148 (14.2%) | 0.009 |
Simultaneous transplant: kidney | 506 (3.6%) | 659 (3.2%) | 16 (1.5%) | 0.001 |
Liver | 27 (0.2%) | 158 (0.8%) | 51 (4.9%) | < 0.001 |