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Table 1 Included study characteris

From: The impact of goal-directed fluid therapy on postoperative pulmonary complications in patients undergoing thoracic surgery: a systematic review and meta-analysis

Trial/author, year [reference]

Sample size

Male/female

Age (y)

Type of surgery

Timing

GDFT technology

Control group

Hemodynamic

monitor

Interventions

Control group

GDFT group

Control group

GDFT group

Xu et al. [13]

168

56/28

54/30

49 ± 5

49 ± 6

Thoracoscopic lobectomy

Intraoperative

10% < SVV < 13% Cardiac index ≥ 2.5L/min/m2

Conventional fluid management according to the principles of Miller’s Anesthesia or used vasoactive substances if necessary

FloT rac/Vigileo device

Fluids, inotropes, and vasopressors

Bahlmann et al. [15]

59

21/8

24/6

66 ± 10

65 ± 7

Ivor Lewis oesophageal resection, McKeown oesophageal resection and left thoraco-abdominal approach

Intraoperative

SV optimisation, Cardiac index ≥ 2.5 L/min/m2

Mean arterial pressure (MAP) of at least 65 mmHg

The responsible anesthetist determined the fluid administration rate and use of vasoconstrictors and inotropes

A FloTrac pressure transducer Vigileo monitor

Fluids, inotropes, and vasopressors

Kaufmann et al. [14]

96

27/21

26/22

65 (55–74)

65 (56–70)

Lung parenchyma resection,via thoracotomy or video-assisted thoracoscopy

Intraoperative

SV optimisation, Cardiac index ≥ 2.5L/min/m2

Mean arterial pressure (MAP) of at least 70 mmHg

Conventional fluid and hemodynamic management according to standard operating procedures

Oesophageal Doppler guided

Fluids, inotropes, and vasopressors

Mukai et al. [19]

232

96

91

36 ± 82

42 ± 83

Open trans-thoracic oesophagectomy or thoraco-laparoscopic oesophagectomy

Intraoperative

SV optimisation, SVV < 12%, SBP > 90 mmHg

Intraoperative hemodynamic management sought to maintain a systolic BP > 90 mm Hg

Vigileo-FloTrac system

Fluids, inotropes, and vasopressors

Zhang et al. [18]

60

14/16

12/18

61.0 ± 8.7

59.9 ± 8.9

Thoracoscopic lobectomy

Intraoperative

GDFT technology

Control group

Vigileo-FloTrac system

Fluids, inotropes, and vasopressors

Wei Tang et al. [20]

65

23/9

28/5

70 ± 5

69 ± 3

Three-stage esophagectomy through the modified McKeown thoracoscopic, laparoscopic and cervical approach

Intraoperative

SVV optimization, SVV < 9%

Conventional fluid management

Pulse-contour analysis catheter (PiCCOâ„¢, pv2014L16-A, 4F)

Fluids, inotropes, and vasopressors